Browse the latest research summaries in the field of musculoskeletal medicine for spinal cord injury patients and caregivers.
Showing 91-100 of 269 results
Cureus, 2022 • December 19, 2022
This case report describes the rehabilitation of a 45-year-old male with paraplegia and an intertrochanteric fracture. The patient had a history of spinal cord injury and sustained the fracture during...
KEY FINDING: Physiotherapy plays a crucial role in the postoperative management of intertrochanteric fractures in paraplegic patients. It helps prevent complications like bed sores, joint stiffness, muscle wasting, and pulmonary issues.
International Journal of Medical Sciences, 2023 • January 31, 2023
The study investigates the role of Numb and Notch signaling in denervation atrophy of skeletal muscle in mice, using nandrolone treatment and conditional knockout models. Results showed that nandrolon...
KEY FINDING: Nandrolone treatment increased Numb expression and reduced Notch signaling in denervated muscle.
Frontiers in Nutrition, 2023 • March 3, 2023
This review summarizes the pathophysiological changes of skeletal muscle atrophy after SCI, analyzes the related factors and atrophy mechanisms, providing a theoretical basis and research direction fo...
KEY FINDING: Inflammation and oxidative stress are major mechanisms driving skeletal muscle atrophy after spinal cord injury.
Bone Reports, 2020 • January 1, 2020
This study introduces a global 2D morphometric analysis step into the μCT analysis process, providing a more systematic approach to VOI selection and enabling the acquisition of additional information...
KEY FINDING: SCI-induced osteoporosis was localized in trabecular bone, with metaphyseal bone more severely affected than epiphyseal bone.
Indian Journal of Orthopaedics, 2020 • June 2, 2020
This randomized controlled trial assessed the effect of early zoledronic acid administration on bone loss in acute SCI patients. aBMD was measured at the forearm at baseline and at 3, 6, and 12 months...
KEY FINDING: Significant differences in aBMD were found between the control and Zoledronic acid groups at various forearm sites in paraplegic patients one year after SCI.
Journal of Orthopaedic Surgery and Research, 2021 • May 5, 2021
This study analyzed the effects of different analgesics on pain and functional recovery in patients with thoracolumbar fractures. Patients were divided into acetaminophen dihydrocodeine, celecoxib, an...
KEY FINDING: Severe spinal cord injury and peri-treatment use of acetaminophen dihydrocodeine were risk factors for postoperative chronic pain.
Neurotrauma Reports, 2021 • January 1, 2021
This study evaluated the adverse effects of high-dose methylprednisolone (MP) administration on bone loss after acute spinal cord injury (SCI) in rats. The results showed that MP significantly reduced...
KEY FINDING: High-dose MP administration significantly reduced bone mineral density (BMD) in the distal femur and proximal tibia of SCI rats compared to SCI-vehicle animals.
Eur J Transl Myol, 2020 • January 22, 2020
The article introduces the collection of abstracts for the “2020 Padua Muscle Days: Mobility Medicine 30 years of Translational Research” conference. The conference addresses the classification and ma...
KEY FINDING: The collection of abstracts highlights translational research involving physical, pharmacological, cellular, and genetic strategies to maintain or rehabilitate skeletal muscle structure and function, and mobility of patients, in aging or premature aging due to diverse diseases.
Spinal Cord, 2020 • March 1, 2020
This study investigated acute changes in the supraspinatus and biceps tendon following fatiguing wheelchair propulsion in persons with spinal cord injury (SCI). The study identified a significant redu...
KEY FINDING: A reduction in supraspinatus tendon thickness after fatiguing wheelchair propulsion was identified.
Frontiers in Rehabilitation Sciences, 2023 • January 26, 2023
This editorial provides an overview of current research in musculoskeletal rehabilitation, focusing on various conditions and novel techniques. Key topics include fear avoidance, adolescent idiopathic...
KEY FINDING: A military fear avoidance questionnaire (RDRQ) shows good correlation with existing scales, suggesting its potential for measuring fear avoidance in active-duty military members.