Browse the latest research summaries in the field of neuroimaging for spinal cord injury patients and caregivers.
Showing 31-40 of 90 results
Sci. Adv., 2020 • August 7, 2020
The study used DTI and NODDI to investigate white matter changes after mTBI, correlating them with neuropsychological performance. Early microstructural white matter changes in mTBI are driven by incr...
KEY FINDING: Early lower fractional anisotropy (FA) and neurite density index (NDI), and early higher mean diffusivity (MD) and free water fraction (FISO) were observed in mTBI patients compared to controls.
Scientific Reports, 2020 • August 5, 2020
This study characterizes neurodegenerative and reorganizational changes across the basal ganglia-thalamic circuit after SCI using advanced neuroimaging measures, in vivo. We demonstrate a dynamic patt...
KEY FINDING: Surface area contracted in the motor (i.e. lower extremity) and pulvinar thalamus, and striatum; and expanded in the motor thalamus and striatum in patients compared to controls over 2-years.
Hum Brain Mapp, 2021 • January 1, 2021
This study validated a simultaneous analysis tool (SPM-BSC) for brain and cervical cord MRI data within the SPM framework, comparing trauma-induced changes in SCI patients to healthy controls. The SPM...
KEY FINDING: The SPM-BSC approach identified trauma-induced changes in the sensorimotor system of the brain and spinal cord in SCI patients, consistent with findings from established analysis methods.
Neurorehabilitation and Neural Repair, 2021 • January 1, 2021
This study assessed the predictive value of midsagittal tissue bridges for American Spinal Injury Association (ASIA) Impairment Scale (AIS) grade conversion and SCI patient stratification into recover...
KEY FINDING: Larger ventral and dorsal tissue bridges were associated with higher AIS conversion rates 12 months post-SCI.
Front. Syst. Neurosci., 2020 • October 21, 2020
This study investigated the relationship between spinal cord MRI markers and the recovery of volitional leg movement with spinal cord epidural stimulation (scES) in individuals with clinically motor c...
KEY FINDING: The amount and location of spared spinal cord tissue at the lesion site were unrelated to the ability to generate volitional lower limb movements with scES.
Biol Psychiatry Cogn Neurosci Neuroimaging, 2021 • March 1, 2021
This study investigated the relationship between regional brain volumes, measured by MRI at 2 weeks post-mTBI, and PTSD outcomes at 3 and 6 months post-injury. Smaller volumes in the insula, superior ...
KEY FINDING: Smaller volumes of the superior frontal, rostral, and caudal anterior cingulate regions were individually predictive of PTSD at 3 months post-injury.
Brain Imaging Behav, 2020 • June 1, 2020
This study introduces a novel method using dMRI tractography to delineate the CST and isolate its hand motor representation (HMFTs). The study quantifies the variability of these tracts in 37 healthy ...
KEY FINDING: The study successfully delineated the CST and HMFTs using a novel dMRI tractography method.
PLoS ONE, 2012 • December 12, 2012
The study investigated the relationship between degeneration of the corticospinal tract (CST) in the cervical cord above a traumatic spinal cord injury (SCI) and its relationship with cervical atrophy...
KEY FINDING: In individuals with SCI, FA was significantly lower in both CSTs throughout the cervical cord and brain when compared with controls.
Arch Phys Med Rehabil, 2015 • April 1, 2015
This pilot study used fMRI to examine cortical activation during a visual illusory walking paradigm in persons with SCI compared to able-bodied controls. The results showed significant activation in t...
KEY FINDING: Persons with SCI showed significant activation in the somatosensory cortex during visually illusory walking.
Ann Rehabil Med, 2015 • June 1, 2015
This study used graph theoretical approaches to assess the efficiency of information processing in the whole brain network of patients with cervical incomplete SCI using rs-fMRI. The study found that ...
KEY FINDING: The normalized characteristic path length to random network was higher in SCI patients than in controls and reached statistical significance at 12%–13% of density.