Browse the latest research summaries in the field of oncology for spinal cord injury patients and caregivers.
Showing 81-90 of 144 results
Advanced Science, 2024 • June 19, 2024
This study reveals that CKB promotes mitochondrial ATP production by inhibiting AKT activation, which in turn reduces mitochondrial calcium levels and mPTP activity. The CKB-AKT signaling axis plays a...
KEY FINDING: CKB is essential for maintaining cellular sensitivity to F1F0 ATP synthase inhibition, a key enzyme in mitochondrial ATP production.
Spinal Cord Series and Cases, 2018 • April 15, 2018
This case report highlights the unique challenges faced by women with spinal cord injuries (SCI) who develop breast cancer, focusing on a 54-year-old woman with a history of traumatic paraplegia who e...
KEY FINDING: Chemotherapy in women with SCI can lead to complications such as reflexive diaphoresis, urinary tract infection, leukopenia, anemia, dehydration, and weakness, contributing to pressure sore development.
ONCOLOGY LETTERS, 2021 • January 1, 2021
The present study aimed to describe the clinical characteristics, and to construct and validate nomograms for patients with non‑metastatic Ewing sarcoma. Age, sex, tumor extension and surgery were in...
KEY FINDING: Age, tumor extension, sex, International Classification of Diseases for Oncology, 3rd Edition histology, surgery and chemotherapy were identified as independent risk factors for OS and CSS.
Journal of Applied Clinical Medical Physics, 2010 • September 1, 2010
The study developed a QA procedure to evaluate the congruence between the CBCT image center and the radiation isocenter without relying on pre-calibrated room lasers or light field crosshairs. The met...
KEY FINDING: The CBCT image center exhibits excellent short-term positional reproducibility, with less than 0.1 mm of wobble in each direction during consecutive acquisitions.
Photoacoustics, 2021 • July 17, 2021
This study focuses on enhancing the photostability of gold nanostars (GNSs) by coating them with silica shells for improved performance in photoacoustic imaging (PAI) and photothermal therapy (PTT). T...
KEY FINDING: Silica-coated GNSs exhibit a threefold improvement in photoacoustic stability compared to uncoated GNSs, making them more reliable for PAI.
Brain Sci., 2024 • December 23, 2024
This review explores radiation-induced brain injury (RIBI), its causes, and potential treatments, with a focus on the gut–brain axis as a therapeutic strategy. RIBI is influenced by treatment, tumor, ...
KEY FINDING: Immunotherapy combined with SRS shows the highest incidence of radiation necrosis (RN) or tumor-related imaging changes compared to targeted therapy and chemotherapy, suggesting a significant correlation between immunotherapy and increased RN rates.
Frontiers in Neurology, 2024 • September 13, 2024
The study identified CELF4 as a central gene associated with immune infiltration among DEGs through bioinformatics analysis of microarray datasets. Previous research indicates that CELF4 may play a cr...
KEY FINDING: A total of 5,151 differentially expressed genes (DEGs) were identified between SP-EP and normal samples. These DEGs are involved in cellular processes like cell cycle regulation and cell sensitivity mechanisms, according to Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis.
Front. Cell. Neurosci., 2018 • October 11, 2018
This study developed a reproducible in vitro model to study MPNST from isolated adult Schwann cells (iSCs) that following transplantation, share striking phenotypic resemblance to primary human MPNST ...
KEY FINDING: Adult rodent Schwann cells can be induced to form MPNST-like tumors after transplantation.
Annals of Rehabilitation Medicine, 2016 • December 1, 2016
This case series reports on the effects of radiation therapy (RT) in three patients with established neurogenic heterotopic ossification (HO) following brain injury. The study found that RT led to dec...
KEY FINDING: Radiation therapy resulted in decreased pain and increased range of motion in patients with established neurogenic heterotopic ossification.
Nat Med, 2016 • July 1, 2016
This study introduces a novel xenotransplantation model using humanized ossicles to improve the engraftment of human hematopoietic cells, including leukemic cells. The humanized ossicles support robus...
KEY FINDING: Humanized ossicles exhibit robust engraftment of normal human hematopoietic stem and progenitor cells.