Browse the latest research summaries in the field of orthopedics for spinal cord injury patients and caregivers.
Showing 211-220 of 352 results
HAND, 2014 • March 4, 2014
The study evaluated surgical procedures to reconstruct pinch and hook functions in tetraplegic patients, comparing different tendon transfer and tenodesis techniques. Results indicated that both BR an...
KEY FINDING: Both brachioradialis (BR) and pronator teres (PT) tendon transfers were equally effective for reconstructing key pinch.
Annals of the Royal College of Surgeons of England, 1984 • January 1, 1984
There has been a world-wide increase in serious neck injuries. Better understanding of the altered physiology of spinal man, and the employment of the appropriate supportive measures, has led to a les...
KEY FINDING: The discovery of any voluntary muscle action below the accepted level of injury is an indication that the lesion is incomplete, with a correspondingly favourable prognosis.
EBioMedicine, 2022 • January 1, 2022
This study investigates the impact of allergy-induced systemic inflammation on tendon quality using a mouse model and human health survey data. The findings demonstrate that allergic inflammation nega...
KEY FINDING: Tendons from allergic mice exhibited a significant reduction in both elastic modulus and tensile stress.
eBioMedicine, 2022 • February 1, 2022
This study investigates the therapeutic efficacy of combining ultra-purified human bone marrow mesenchymal stem cells (RECs) and a bioresorbable gel for IVD regeneration after discectomy in a sheep mo...
KEY FINDING: Co-culturing RECs and nucleus pulposus cells (NPCs) in the gel significantly increased gene expression of NPC markers, growth factors, and extracellular matrix compared to monocultures.
JOR Spine, 2022 • January 1, 2022
Intradiscal injection is a minimally invasive technique used for low back pain, with its safety and effectiveness supported by clinical trials. Various medications and biological agents are used, but ...
KEY FINDING: Intradiscal injection is a minimally invasive outpatient procedure that can improve pain quality for patients with LBP or lumbar disc herniation (LDH).
European Journal of Trauma and Emergency Surgery, 2022 • May 21, 2022
This retrospective cohort study aimed to differentiate geriatric odontoid fractures into stable (SFs) and unstable fractures (UFs) based on angulation and displacement, correlating this classification...
KEY FINDING: The classification into SFs and UFs was significant for its angulation (P = 0.0006) and displacement (P < 0.0001).
BMC Musculoskeletal Disorders, 2022 • June 3, 2022
This study compared two methods (GVR-A and GVR-B) for evaluating spinal cord hyperechogenicity intensity using intraoperative ultrasound (IOUS) in patients with degenerative cervical myelopathy (DCM) ...
KEY FINDING: GVR-B has better repeatability of gray value measurement, smaller relative standard deviation (RSD%) compared with GVR-A.
Cureus, 2022 • June 16, 2022
This review compiles recent data on collagen scaffolds for treating SCI in animal models. SCI presents significant challenges due to its economic and psychological impact. Studies using animals with s...
KEY FINDING: Collagen-based scaffolds, when transplanted, showed the most proliferation, and neural stem and progenitor cells survived up to 11 weeks after the transplant.
Frontiers in Neurology, 2022 • August 17, 2022
This review discusses the principles of ESWT, its cellular and molecular mechanisms, and its application in treating central and peripheral nervous system diseases based on animal and clinical studies...
KEY FINDING: ESWT can promote neural tissue regeneration and repairment in both the central and peripheral nervous systems, as demonstrated in animal studies of sciatic nerve injury, cerebral infarction, and spinal cord injury.
Orthopaedic Surgery, 2022 • December 1, 2022
This review synthesizes current research on resveratrol's (RSV) effects on intervertebral disc degeneration (IDD). It highlights RSV's potential to address the limitations of current IDD treatments by...
KEY FINDING: RSV exhibits anti-inflammatory effects by inhibiting pro-inflammatory cytokines like IL-1β, IL-6, IL-8, and TNF-α, which ameliorates IDD progression mediated by inflammation.