Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 131-140 of 555 results
Frontiers in Pain Research, 2021 • July 12, 2021
This case report explores the use of conditioning open-label placebo (COLP) as a pharmaco-behavioral intervention to reduce opioid dosage and side effects after inpatient rehabilitation discharge. The...
KEY FINDING: The patient could discontinue oxycodone intake (a reduction from 15 morphine equivalents/day) after rehabilitation discharge following COLP treatment.
Therapeutic Advances in Chronic Disease, 2022 • January 12, 2022
This systematic review and meta-analysis evaluated the effectiveness of physiotherapy interventions for managing central neuropathic pain (cNeP) from any cause. The study included 23 randomised contro...
KEY FINDING: Non-invasive neurostimulation was found to reduce pain severity due to spinal cord injury and phantom limb pain.
Neurosci. Bull., 2022 • April 9, 2022
This study characterized the analgesic effect of spinal cord stimulation (SCS) in a rat model of neuropathic pain, focusing on the involvement of opioid peptides. The study explored the impact of sti...
KEY FINDING: The analgesic effect of SCS is more effective in rats with moderate, rather than severe, mechanical hypersensitivity.
Spinal Cord Series and Cases, 2022 • March 29, 2022
This case report investigated the long-term effects of physical therapy, including intensive gait training, on neuropathic pain and peak alpha frequency (PAF) in a patient with cervical spinal cord in...
KEY FINDING: NRS scores for the mean and maximum intensities of pain decreased significantly after 6 weeks of physical therapy.
Spinal Cord, 2022 • April 12, 2022
The study successfully translated and adapted the SCIPI for use in Brazil. The adapted SCIPI demonstrated strong reliability and validity in assessing neuropathic pain among individuals with spinal co...
KEY FINDING: The Brazilian version of the SCIPI demonstrated adequate structural validity, confirming its one-dimensional structure.
Sensors, 2022 • March 29, 2022
This study investigates the impact of virtual reality (VR) on neuropathic pain (NP) in individuals with spinal cord injury (SCI) by analyzing changes in brain activity using electroencephalography (EE...
KEY FINDING: There was an increase in delta activity in frontal regions for 3D VR with a decrease in theta activity.
Arq Neuropsiquiatr, 2022 • March 1, 2022
The study investigates the mechanism by which electroacupuncture (EA) provides analgesia for neuropathic pain, focusing on the role of ecto-5’-nucleotidase (5’-NT). Results indicate that EA upregulate...
KEY FINDING: Electroacupuncture (EA) increases the expression of ecto-5’-nucleotidase (5’-NT) in the spinal cord of rats with chronic constriction injury (CCI).
Oxidative Medicine and Cellular Longevity, 2022 • February 14, 2022
The study aimed to explore the mechanisms through which EA ameliorates pain in a rat CRPS-I model, focusing on potential substances or biological processes affected during CRPS-I. The research identif...
KEY FINDING: Oxidative stress primarily occurs in local hindpaw tissues of CPIP rats and contributes to mechanical allodynia.
Rehabil Psychol, 2022 • August 1, 2022
This study examined the relationships among pain, mental health symptom severity, life satisfaction, and understanding from others in veterans with SCI. The findings indicated that pain and understand...
KEY FINDING: Pain was significantly associated with increased mental health symptom severity in veterans with SCI.
Journal of Pain Research, 2022 • May 5, 2022
This study demonstrated that Z-guggulsterone significantly alleviated mechanical and thermal hyperalgesia induced by CCI in mice. The study observed that Z-guggulsterone inhibited astrocytes activatio...
KEY FINDING: Z-guggulsterone significantly reduced mechanical and thermal hyperalgesia (increased sensitivity to pain) in mice with CCI.