Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 121-130 of 555 results
Redox Biology, 2022 • January 1, 2022
This study investigates the role of Dynamin-related protein 1 (Drp1), a key regulator of mitochondrial fission, in neuropathic pain (NP) using a spared nerve injury (SNI) model in mice. The research f...
KEY FINDING: SNI in mice induces pain behavior and anxiety-like behavior, which is associated with elevation of Drp1, as well as increased density of mitochondria in SDH.
Medicine, 2021 • December 2, 2021
The case report describes a 46-year-old woman with chronic low back pain and chronic pelvic pain (CPP) following multiple pelvic fractures, who experienced significant pain relief and improved quality...
KEY FINDING: Two weeks after the intervention a reduction of 80% of the pain was achieved, which led to the removal of the pharmacologic treatment.
Molecular Pain, 2022 • January 1, 2022
The study evaluated the effect of differential target multiplexed programming (DTMP) spinal cord stimulation (SCS) on proteins involved in ion transport regulation in the spinal cord of rats with neur...
KEY FINDING: DTMP modulated a larger number of proteins involved in ion transport regulation compared to LR SCS.
Spinal Cord, 2022 • February 1, 2022
Adults with traumatic SCI are at increased risk for developing both general psychological morbidity as well as most specific psychological conditions. Chronic centralized and neuropathic pain is robus...
KEY FINDING: Adults with SCI had a higher incidence of psychological morbidities compared to those without SCI.
Sensors, 2022 • January 10, 2022
This study introduces a fully implantable, miniaturized spinal cord stimulator based on liquid crystal polymer (LCP) for pain control. The device addresses limitations of conventional metal-packaged s...
KEY FINDING: The LCP-based spinal cord stimulator effectively suppressed pain in a rat model of spared nerve injury.
Spinal Cord Series and Cases, 2022 • January 14, 2022
This survey-based study investigates the demographics of pain following spinal cord injury (SCI), utilizing standardized pain assessment tools to characterize pain types and severities in relation to ...
KEY FINDING: 81% of individuals with SCI experience chronic pain, and 86% of those with pain have neuropathic pain.
Spinal Cord, 2022 • February 5, 2022
The objective was to update the 2016 version of the Canadian clinical practice guidelines for the management of neuropathic pain in people with spinal cord injury (SCI). The working group identified an...
KEY FINDING: The panel agreed on three new screening and diagnosis recommendations, and eight new treatment recommendations. No new model of care recommendations were proposed as no relevant articles were identified.
Frontiers in Neuroscience, 2022 • February 11, 2022
This systematic review and network meta-analysis evaluated the effect of non-invasive brain stimulation (NIBS) on neuropathic pain (NP) after spinal cord injury (SCI) and compared the effects of two d...
KEY FINDING: NIBS can reduce the pain score in patients with neuropathic pain after spinal cord injury. The meta-analysis showed that the pain score of the NIBS group was lower than that of the control group.
Spinal Cord, 2022 • March 11, 2022
This meta-analysis evaluated the efficacy of TENS for pain relief in individuals with SCI, incorporating data from six studies. The results indicate that TENS can improve pain symptoms, as evidenced b...
KEY FINDING: TENS was found to significantly reduce pain as measured by the visual analog scale (VAS) in patients with spinal cord injury.
BMJ Open, 2022 • January 1, 2022
This study protocol outlines a clinical trial comparing rTMS in the DLPFC versus M1 for neuropathic pain after SCI. The study will recruit 50 participants and assess pain, sleep, and anxiety levels ov...
KEY FINDING: The study is designed to compare the efficacy of rTMS on the DLPFC with the motor cortex (M1) in NPP after SCI.