Pharmacology Research

KEY FINDING: A 31-year-old man developed left brachial plexopathy after CO poisoning, confirmed by electrophysiological studies showing severe abnormalities in the upper and moderate abnormalities in the middle branches.

KEY FINDING: Tea-Seed Oil (TSO) contains components with antibacterial properties, potentially acting through pathways like PI3K-AKT and MAPK.

KEY FINDING: The pathophysiology of SCI consists of a two-phase process: the primary mechanical injury and the subsequent cascade of auto-destructive damages. This cascade leads to inflammation, hemorrhage, demyelination, axon disruption, apoptosis, and necrosis.

KEY FINDING: Both Deanxit and NeuroWell reduced the Hamilton anxiety scale and Hamilton depression scale scores compared to the placebo.

KEY FINDING: HCPs identified AOM side effects (bowel problems, gastrointestinal distress, skin breakdown, muscle loss) as significant barriers due to potential exacerbation in SCI/D patients.

KEY FINDING: BTX might exert a direct influence on bone resorption.

KEY FINDING: Boldine blocks connexin (Cx) hemichannels (HCs), and many of its effects in rodent models are attributed to this blockade.

KEY FINDING: MCPP-M-gel demonstrated favorable physico-mechanical properties and extended MC release over 72 hours in vitro without cytotoxic effects on neural crest-derived ectoderm mesenchymal stem cells (EMSCs).

KEY FINDING: The final concept map included eight clusters, each representing a key content area for the medication self-management toolkit.

KEY FINDING: The combined protocol of nighttime oxygen with high flow cannula and daytime Venturi mask improves intensive motor training of patients.