Browse the latest research summaries in the field of physiology for spinal cord injury patients and caregivers.
Showing 81-90 of 292 results
Frontiers in Physiology, 2021 • February 4, 2021
The study evaluated the effects of rTMS on rat gait function under simulated microgravity (SM) conditions. SM was induced for 21 days, with rTMS applied for 14 days starting on the eighth day of SM. B...
KEY FINDING: SM could cause gait disorders such as decreased walking ability and contralateral limb imbalance in rats, which could be reversed by rTMS.
Top Spinal Cord Inj Rehabil, 2021 • January 1, 2021
Individuals with SCI are at risk for neurogenic obesity due to changes in body composition, reduced physical activity, and metabolic dysfunction. Accurate assessment of metabolic rate is crucial to pr...
KEY FINDING: Measured metabolic rate is lower in persons with SCI compared to the nondisabled population, ranging from 1256 to 1854 kcal/day for individuals with longstanding SCI.
J Korean Neurosurg Soc, 2021 • March 1, 2021
Intraoperative neurophysiological monitoring (IONM) is crucial during untethering surgery for spinal dysraphism to minimize neurological risks and maximize surgical efficacy. Key IONM modalities inclu...
KEY FINDING: Free-running EMG and triggered EMG are highly useful for identifying lumbosacral roots during surgery.
Scientific Reports, 2021 • January 26, 2021
This study presents a high-resolution comparative atlas of the lumbosacral spinal cord in rats, cats, pigs, monkeys, and humans, detailing the location, length, cross-sectional area, and morphology of...
KEY FINDING: The lumbar enlargement spans different spinal cord levels in each species: L3-S1 in rats, L4-S1 in cats, L3-S1 in pigs, L2/L3-L7/S1 in monkeys, and T12/L1-S1/S2 in humans.
Scientific Reports, 2019 • December 19, 2019
The study analyzed blood pressure (BP) and heart rate (HR) responses to electrical stimulations at each DCN from T6 to L1 at 0.5 mA to activate A-fiber alone or 5 mA to activate both A- and C-fibers a...
KEY FINDING: Stimulation strength showed a large effect on BP changes dependent on C-fibers whereas HR changes were dependent on A-fibers.
J Physiol, 2021 • August 1, 2021
Passive skeletal muscle mechanical properties of whole muscle are not as well understood as muscle’s active mechanical properties. Future studies defining the specific load bearing structures and thei...
KEY FINDING: Titin bears the majority of passive load within the single muscle cell.
GeroScience, 2021 • April 24, 2021
This study provides direct evidence for NMJ dysfunction as a potential mechanism of age-related muscle dysfunction pathogenesis and severity in rats. The findings suggest that modulation of NMJ transm...
KEY FINDING: Aged rats exhibited significant declines in NMJ transmission stability and reliability, as measured by SFEMG and RNS.
Bioengineering, 2023 • February 6, 2023
This study examined central neural and peripheral muscle changes after a spinal cord injury (SCI) using surface electromyography (EMG). MFCV was found to be significantly slower in the SCI group than ...
KEY FINDING: Muscle fiber conduction velocity (MFCV) was significantly slower in the SCI group than the control group at all force levels.
PLoS ONE, 2021 • May 7, 2021
This scoping review mapped the evidence on measurement properties of body composition tools to assess whole-body and regional fat and fat-free mass in adults with SCI, and to identify research gaps in...
KEY FINDING: Whole-body DXA is the only tool supported by studies showing both acceptable test-retest reliability and convergent validity for assessing body composition in SCI.
JOURNAL OF NEUROTRAUMA, 2019 • September 15, 2019
This study used metabolomics to investigate changes in muscle metabolites after spinal cord injury (SCI) in mice, focusing on acute (7-day) and subacute (28-day) time frames. The results showed that k...
KEY FINDING: Glucose, lactic acid, and pyruvic acid levels are reduced in paralyzed skeletal muscle at 7 days post-SCI, indicating a disruption in glucose uptake.