Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.
Showing 561-570 of 607 results
Nucleic Acids Research, 2023 • November 1, 2022
The Human Universal Single Cell Hub (HUSCH) is introduced as a curated database integrating single-cell transcriptomic profiles from nearly 3 million cells across 45 human tissues. HUSCH uniformly pro...
KEY FINDING: HUSCH integrates single-cell transcriptomic profiles of nearly 3 million cells from 185 high-quality human scRNA-seq datasets across 45 different tissues.
Behavioral and Brain Functions, 2013 • June 7, 2013
The study evaluated the impact of environmental enrichment or impoverishment in mice three months after induction of chronic neuropathic pain. Environmental enrichment attenuated nerve injury-induced ...
KEY FINDING: Environmental enrichment attenuated nerve injury-induced hypersensitivity to mechanical and cold stimuli.
BMC Geriatrics, 2016 • February 26, 2016
This study evaluated different strategies for classifying “does not do” responses to IADL questions when estimating prevalence of IADL limitations in a national survey. IADL stage prevalence estimates...
KEY FINDING: IADL stage prevalence estimates differed little across the four alternative strategies.
Journal of Neurochemistry, 2025 • February 3, 2025
The study introduces a novel tamoxifen-inducible PDGFRβ+ cell ablation model in mice to investigate pericyte responses in the CNS following acute ablation, addressing limitations in existing models. T...
KEY FINDING: A low dose of tamoxifen effectively ablates PDGFRβ+ cells of the CNS in mice without reducing survival or causing significant systemic side effects, such as weight loss.
Arch Phys Med Rehabil., 2019 • May 1, 2019
This study demonstrates inconsistencies in the documentation of data elements in 5 common trauma databases. These discrepancies are a barrier to database harmonization and to maximizing the use of the...
KEY FINDING: Of the 30 data elements examined, 14 (47%) were present in all 5 databases.
J Spine Surg, 2018 • June 1, 2018
This case report describes a rare complication of total lumbar disc replacement (TDR), where the viscoelastic nucleus of the artificial disc herniated, causing nerve compression and radiculopathy. The...
KEY FINDING: The case report presents an unreported complication of lumbar TDR involving herniation of the viscoelastic nucleus, mimicking a disc herniation.
Neural Plasticity, 2016 • April 18, 2016
This review explores the remarkable regenerative capacity of the zebrafish central nervous system (CNS), focusing on spinal cord repair. Unlike mammals, zebrafish can regenerate damaged spinal cords, ...
KEY FINDING: Zebrafish spinal cord regeneration involves a brief inflammatory response, macrophage activity to clear myelin debris, minimal cell loss, extensive neurogenesis, and a permissive environment for axonal regrowth.
Journal of Medical Case Reports, 2022 • November 30, 2022
This case report describes an 81-year-old man who developed unilateral delayed post-hypoxic leukoencephalopathy (DPHL) following a dissection-related occlusion of the left carotid artery. The patient ...
KEY FINDING: Clinical symptoms suggestive of delayed post-hypoxic leukoencephalopathy (DPHL) can be observed in very rare cases following successful revascularization therapy in large vessel occlusions, causing acute ischemic stroke.
BMC Res Notes, 2017 • January 18, 2017
This case report highlights the diagnostic challenges of cobalamin deficiency, particularly in patients with SACD, and emphasizes the importance of considering alternative markers like MMA and homocys...
KEY FINDING: Normal cobalamin serum levels do not rule out a cobalamin deficiency, especially in cases of SACD.
Annals of Rehabilitation Medicine, 2014 • August 1, 2014
This study aimed to determine the effect of combined cervical radiculopathy on the prognosis of patients with traumatic cervical spinal cord injury (SCI). The study found that a significant proportion...
KEY FINDING: Almost half (48.5%) of the cervical SCI patients also had cervical radiculopathy.