Browse the latest research summaries in the field of spinal cord injury for spinal cord injury patients and caregivers.
Showing 2,781-2,790 of 7,662 results
Medicine, 2021 • January 1, 2021
This case report details the surgical management of a 53-year-old male with complete spinal cord transection at the T11-T12 level due to a traumatic fracture-dislocation. The surgical intervention inc...
KEY FINDING: The study reports the intraoperative finding and management of complete spinal cord transection in thoracolumbar spine injury, which is rare in reported cases.
European Journal of Trauma and Emergency Surgery, 2019 • August 24, 2018
Cervical spine injuries in children, though rare, carry the potential for severe neurological sequelae, necessitating exceptional management from initial assessment to rehabilitation. Key consideratio...
KEY FINDING: Upper cervical spine injuries are more common in younger children (≤ 8 years), while lower cervical spine injuries are more prevalent in older children (> 8 years).
Cells, 2019 • December 6, 2019
This study investigates the therapeutic potential of dabrafenib, a B-RAFV600E inhibitor, in attenuating RIPK3-mediated necroptosis and promoting functional recovery after spinal cord injury (SCI) in a...
KEY FINDING: Dabrafenib administration significantly inhibited RIPK3-mediated necroptosis in the injured spinal cord, reducing the expression of RIPK3 and phosphorylated MLKL (pMLKL).
PLoS Medicine, 2023 • November 27, 2023
This systematic review and meta-analysis confirms that exercise interventions lasting >2 weeks improve CRF in individuals with SCI. The pooled meta-analysis revealed that interventions up to 12 weeks,...
KEY FINDING: Performing exercise >2 weeks results in significant improvements to A _VO2peak, R _VO2peak, and PPO in individuals with SCI.
Front. Syst. Neurosci., 2021 • January 5, 2021
The study investigated the effects of activity-based recovery training with epidural stimulation (ABRT-scES) on bladder function in individuals with chronic spinal cord injury (SCI). Results showed im...
KEY FINDING: Activity-based recovery training with scES improved bladder capacity relative to baseline and to a usual care cohort.
JOURNAL OF NEUROTRAUMA, 2019 • September 15, 2019
This study used metabolomics to investigate changes in muscle metabolites after spinal cord injury (SCI) in mice, focusing on acute (7-day) and subacute (28-day) time frames. The results showed that k...
KEY FINDING: Glucose, lactic acid, and pyruvic acid levels are reduced in paralyzed skeletal muscle at 7 days post-SCI, indicating a disruption in glucose uptake.
The Journal of Spinal Cord Medicine, 2020 • January 1, 2020
This study aimed to identify and analyze the top 100 most influential clinical research articles on traumatic spinal cord injury (SCI) through citation analysis using the Web of Science database. The ...
KEY FINDING: Archives of Physical Medicine and Rehabilitation was the most represented journal, with 20 of the top 100 articles, followed by Spinal Cord and Journal of Neurosurgery.
Cells, 2022 • September 30, 2022
This review examines the potential of activity-based interventions (ABI) to alleviate neuropathic pain (NP) following spinal cord injury (SCI) in preclinical rodent models. It focuses on molecular and...
KEY FINDING: Weight-bearing rhythmic activity-based paradigms seem effective for neuropathic pain relief after spinal cord injury, regardless of whether interventions are started early or delayed, or applied for short or long durations, but the benefits may not persist long after halting the interventions.
Bioengineering, 2022 • December 3, 2022
This study investigates the feasibility of using the Xiaomi Mi Band 5 (XMB5), a low-cost wearable sensor, for heart rate (HR) monitoring during upper limb (UL) training in patients with cervical spina...
KEY FINDING: There was a strong and positive correlation (r = 0.921 and r = 0.941, p < 0.01) between HR measurements from the Xiaomi Mi Band 5 (XMB5) and the Nonin LifeSense II (NLII) devices in healthy individuals during static and dynamic conditions, respectively.
The Journal of Spinal Cord Medicine, 2019 • January 1, 2019
This study documents bladder management practices among SCI patients in Pakistan, highlighting the preference for CIC but also the common practice of reusing disposable catheters due to cost. The stud...
KEY FINDING: CIC was the preferred method of bladder management, followed by indwelling Foley catheters.