Browse the latest research summaries in the field of spinal cord injury for spinal cord injury patients and caregivers.
Showing 7,641-7,650 of 7,662 results
Cell Mol Neurobiol, 2010 • July 14, 2010
This is a retraction note for an article originally published online on July 14, 2010, in Cellular and Molecular Neurobiology. The reason for the retraction is the duplication of a significant amount ...
KEY FINDING: The original article (DOI 10.1007/s10571-009-9449-4) has been retracted.
J Spinal Cord Med, 2006 • January 1, 2006
This case report describes a 21-year-old man with a C6 spinal cord injury who developed adrenal insufficiency two weeks after the injury. The patient's adrenal insufficiency complicated his rehabilita...
KEY FINDING: The patient developed symptomatic hypotension resistant to vasopressors and volume replacement 2 weeks after injury and was diagnosed with adrenal insufficiency.
Frontiers in Aging Neuroscience, 2022 • December 7, 2022
This review synthesizes recent advances in understanding the immune response following spinal cord injury (SCI), highlighting the dual roles of various immune components in either promoting or hinderi...
KEY FINDING: Glial cells in the spinal cord, like astrocytes and microglia, are not just supportive cells but also key players in the immune response after SCI, influencing inflammation and tissue repair.
Exp Neurol, 2016 • August 1, 2016
This study investigates the remote effects of thoracic spinal cord injury (SCI) on the lumbar region, focusing on myeloid cell infiltration and its impact on locomotor networks. The findings reveal th...
KEY FINDING: Myeloid cell infiltration occurs in the lumbar cord, but not the cervical region, after thoracic SCI.
Nature Communications, 2019 • September 6, 2019
The spinal injury scar is a complex entity comprising various cell types and extracellular components that interplay to modulate tissue repair and regeneration after spinal cord injury. Reactive astro...
KEY FINDING: The spinal injury scar comprises multiple cellular and extracellular components beyond just glial cells, including fibroblasts, immune cells, and extracellular matrix.
J Neuropathol Exp Neurol, 2013 • November 1, 2013
This study investigates the involvement of kallikreins (KLKs) in traumatic spinal cord injury (SCI) by examining their expression patterns in human and murine SCI models, as well as their effects on n...
KEY FINDING: Temporally and spatially distinct changes in kallikrein expression were observed with partially overlapping patterns between human and murine SCI, including peak elevations (or reductions) during the acute and subacute periods.
J Spinal Cord Med, 2009 • April 1, 2009
This case report describes a patient with chronic SCI who presented with severe fatigue and was diagnosed with severe dilated cardiomyopathy. The patient's multiple risk factors, including obesity, sm...
KEY FINDING: The patient had a 2-year history of progressive severe fatigue, obesity, hypertension, tachycardia, and pitting edema.
Top Spinal Cord Inj Rehabil, 2016 • January 1, 2016
This qualitative study highlights the importance of addressing health-related issues and teaching health management skills to enhance individuals’ employment outcomes across their work lifecycle. Imme...
KEY FINDING: Individuals with SCI need to relearn how their body works to return to work and develop routines that support employment.
Neural Regeneration Research, 2018 • May 1, 2018
Fatigability, encompassing both performance decline and altered sensations, significantly challenges individuals with spinal cord injuries (SCI) by disrupting metabolic homeostasis due to cardiorespir...
KEY FINDING: Individuals with incomplete SCI experience elevated feelings of tiredness following prolonged self-selected volitional treadmill walking, unlike able-bodied individuals.
BMC Neuroscience, 2018 • February 27, 2018
The study presents AxonTracer, a novel open-source ImageJ plugin for automated analysis of regenerating axons in spinal cord tissue. AxonTracer provides an interactive user interface, allowing for par...
KEY FINDING: AxonTracer correlates strongly with semi-manual quantification by NeuronJ, a widely used ImageJ plugin, but with full automation and reduced user input.