Browse the latest research summaries in the field of spinal cord injury for spinal cord injury patients and caregivers.
Showing 7,631-7,640 of 7,662 results
Brain and Spine, 2025 • January 23, 2025
This study comprehensively examines the temporospatial dynamics of vascular injury and regeneration following experimental spinal cord injury (SCI) in mice, focusing on changes in vascular density, pe...
KEY FINDING: Vascular injury is most severe initially at the epicenter and spreads to surrounding spinal cord regions, with a delayed vascular loss observed in peritraumatic regions.
Eur J Neurosci, 2009 • January 1, 2009
This study investigated whether a coculture of endothelial cells (ECs) and neural progenitor cells (NPCs) in a biodegradable implant could promote angiogenesis and formation of the blood-spinal cord b...
KEY FINDING: The coculture implant led to a four fold increase in functional vessels compared to the lesion control, implant alone, or implant plus NPCs groups.
Neural Regen Res, 2018 • May 1, 2018
This study demonstrates that endothelial progenitor cell-conditioned medium (EPC-CM) exerts anti-inflammatory effects, promotes angiogenesis, and provides neuroprotection in a rat model of spinal cord...
KEY FINDING: EPC-CM reduces inflammation by decreasing M1 macrophage activation and the release of pro-inflammatory cytokines.
J Spinal Cord Med, 2007 • January 1, 2007
This study evaluated complications in 194 spinal cord injury (SCI) patients following the 2005 earthquake in Northern Pakistan. The most common complications observed were urinary tract infections, pr...
KEY FINDING: All patients developed urinary tract infections (UTIs).
The Journal of Spinal Cord Medicine, 2016 • May 1, 2016
This study evaluated the impact of the 2013 revision of the ISNCSCI worksheet on classification performance by comparing it to the 2011 version. The results indicated that the 2013 revision led to a s...
KEY FINDING: The 2013 worksheet revision significantly improved overall classification performance compared to the 2011 revision.
Spinal Cord Series and Cases, 2018 • February 19, 2018
This case report presents a 34-year-old male, 12 years post-cervical spinal cord injury, who underwent nerve transfer surgery to restore hand function. The surgery involved transferring a branch of th...
KEY FINDING: Nerve transfers can successfully restore volitional hand function even more than 10 years following SCI.
Annals of Rehabilitation Medicine, 2014 • June 1, 2014
This study characterized neuropathic pain in SCI patients using the Baron classification. The most common pain characteristic was pricking pain, followed by electrical pain and numbness. The study fou...
KEY FINDING: Pricking pain was the most common pain characteristic among SCI patients with neuropathic pain, followed by electrical pain and numbness.
Frontiers in Neurorobotics, 2018 • August 10, 2018
This study designed an artificial neural network (ANN) to predict torque exerted around the knee joint by the quadriceps muscle using mechanomyography (MMG) parameters during FES isometric knee extens...
KEY FINDING: ANN models using MMG data (RMS and RMS-ZC) can predict knee extension torque during FES with reasonable accuracy.
Arch Phys Med Rehabil, 2007 • May 1, 2007
The study aimed to determine the frequency, severity, and course of seven symptoms in individuals with spinal cord injury (SCI) and their association with patient functioning. Postal surveys were used...
KEY FINDING: Pain, weakness, fatigue, and numbness were the most frequently reported symptoms among individuals with SCI.
FEBS Open Bio, 2022 • January 1, 2022
This study identifies differentially-expressed innate immune-related genes and hub genes following spinal cord injury (SCI). Temporal expression patterns of these genes were analyzed and validated to ...
KEY FINDING: Nine hub genes (Ccl2, Stat3, Mapk14, Stat1, Tlr2, Cxcl10, Myd88, Itgam, and Mapk8) were identified as key players in the innate immune response after SCI.