Browse the latest research summaries in the field of spinal disorders for spinal cord injury patients and caregivers.
Showing 71-80 of 104 results
Journal of Orthopaedic Surgery and Research, 2025 • February 10, 2025
This study retrospectively analyzed 22 patients with severe post-tubercular kyphosis (PTK) who underwent modified posterior vertebral column resection (mPVCR). The results demonstrated significant imp...
KEY FINDING: The modified PVCR technique resulted in a significant improvement in kyphosis angle (KA) from 129.5° to 43.7° postoperatively.
Oxidative Medicine and Cellular Longevity, 2022 • October 11, 2022
This study used bioinformatics analysis to identify genes associated with mitochondrial dysfunction in intervertebral disc degeneration (IDD). Datasets GSE70362 and GSE124272 were downloaded from the ...
KEY FINDING: Identified 152 differentially expressed genes (DEGs) between IDD patients and healthy controls, including 67 upregulated and 85 downregulated genes.
Journal of Orthopaedic Surgery and Research, 2025 • January 16, 2025
This study investigated the impact of simulated overload and microgravity on intervertebral disc degeneration in rabbits. The researchers focused on the expression of MMP1, MMP3, and TIMP1. The study ...
KEY FINDING: MMP1 and MMP3 expression increased significantly in experimental groups compared to controls. The increase correlated with longer exposure to simulated overload and microgravity.
Int. J. Mol. Sci., 2023 • April 21, 2023
This review examines the current literature on basic research and emerging clinical applications of PRP therapy for treating spinal diseases, covering in vitro and in vivo studies evaluating PRP's pot...
KEY FINDING: Basic research indicates PRP has promising regenerative potential for intervertebral disc degeneration based on in vitro and in vivo studies.
BMC Musculoskeletal Disorders, 2024 • August 19, 2024
The study aimed to assess biomechanical changes resulting from OLIF combined with six different internal fixation methods for degenerative spondylolisthesis in the lumbar spine using finite element an...
KEY FINDING: The S-A model had the highest average ROM of six motion modes, followed by LSR, UPS, UCBT, BPS and BCBT.
Journal of Orthopaedic Case Reports, 2025 • February 1, 2025
Spinal cord injury (SCI) is most common following trauma, typically involving motor vehicle incidents. The clinical prognosis depends on many factors, most importantly the initial grade of injury. We ...
KEY FINDING: A computed tomography scan demonstrated cervicomedullary transection caused by C6-C7 facet distraction with C6 retrolisthesis on C7.
Cureus, 2025 • March 9, 2025
This case report describes a 72-year-old male who developed white cord syndrome (WCS) after undergoing posterior cervical laminectomy and fusion for cervical stenosis due to ossification of the poster...
KEY FINDING: The patient developed WCS after posterior cervical decompression and fusion for cervical stenosis caused by ossification of the posterior longitudinal ligament (OPLL).
Pain Ther, 2021 • September 15, 2021
The study investigated the impact of pedicle screw insertion trajectory on disc height recovery after fusion surgery for degenerative lumbar spondylolisthesis (DLS). The results suggest that the Cauda...
KEY FINDING: Changes in disc height (DH) were significantly associated with lower pedicle screw angle.
Spine Deformity, 2025 • September 4, 2024
This case report describes a rare instance of delayed neurological deficit six years after adolescent idiopathic scoliosis (AIS) surgery, caused by a medially misplaced thoracic pedicle screw followin...
KEY FINDING: A medially misplaced T8 pedicle screw, previously asymptomatic, caused a delayed neurological deficit six years after scoliosis surgery following a motor vehicle collision.
Journal of Orthopaedic Surgery and Research, 2024 • December 1, 2024
This retrospective study analyzed 90 adult patients with severe rigid scoliosis (SRS) who underwent posterior column osteotomy (PCO) and fusion to identify risk factors for postoperative coronal imbal...
KEY FINDING: Preoperative coronal imbalance (CIB+) is significantly associated with postoperative CIB [OR = 12.414 (95% CI: 2.228, 69.162), P = 0.004].