Browse our collection of 11,526 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 3,861-3,870 of 11,526 results
International Journal for Equity in Health, 2021 • December 1, 2021
This study aimed to understand the pathways through which SES influences loneliness in a large sample of persons with physical disabilities, namely SCI. This study highlighted the importance of second...
KEY FINDING: The study demonstrated robust associations between socioeconomic status and all potential mediators, whereby higher socioeconomic status was associated with better health, participation and psychosocial resources.
Journal of Frailty, Sarcopenia and Falls, 2021 • December 1, 2021
Osteosarcopenia has been proposed as a syndrome in a subset of frail individuals at higher risk of falls, fractures and institutionalization. A new holistic concept called Osteosarcopenia School will ...
KEY FINDING: Osteosarcopenia and osteosarcopenia with a severe sarcopenia component may occur in both osteoporotic and osteopenic individuals, increasing symmetrically fracture risk.
Journal of NeuroEngineering and Rehabilitation, 2021 • December 1, 2021
This feasibility study evaluated the use of a free-standing robotic exoskeleton (REX) for physiotherapy in patients with spinal cord injury (SCI). The study assessed the acceptability, recruitment rat...
KEY FINDING: The study demonstrated that a 12-week intervention program using a free-standing exoskeleton for weightbearing exercise in those with severe mobility impairment, as a result of SCI, is acceptable, safe and achievable.
Cell J, 2021 • December 1, 2021
This study investigated the neuroprotective effects of methylprednisolone (MP) and fluoxetine (FLX) in a rat model of spinal cord injury (SCI) with induced hypothyroidism. The researchers examined the...
KEY FINDING: The combined treatment with MP and FLX significantly decreased the expression levels of TNF-α and IL-6 in rats with SCI and hypothyroidism.
Neurology: Clinical Practice, 2021 • December 1, 2021
The commentary addresses the disparities and increased risk of traumatic spinal cord injury that Black Americans face due to violence. It highlights inequities in rehabilitation services, medical care...
KEY FINDING: Black Americans experience a disproportionately high rate of spinal cord injuries due to violence, nearly double the percentage of the Black population in the United States.
Molecular Therapy: Methods & Clinical Development, 2021 • December 1, 2021
This study reports the unexpected finding that AAV vectors accumulate in the pineal gland following injections into the brain, spinal cord, or cerebrospinal fluid (CSF). Different AAV serotypes, inclu...
KEY FINDING: AAV vectors accumulate in the pineal gland following injections into the brain, spinal cord, or cerebrospinal fluid.
Neural Regeneration Research, 2021 • December 1, 2021
This study investigates the interaction between spastin and CRMP3 in spinal cord injury repair, finding that CRMP3 expression is inversely associated with SCI severity. The research demonstrates that ...
KEY FINDING: Mass spectrometry identified the role of CRMP3 in the spinal cord injury repair process.
Exp Neurol, 2021 • December 1, 2021
This study demonstrates that phrenic motor neurons (PMNs) survive after cervical spinal cord hemisection (C2Hx) in rats, challenging previous findings suggesting substantial motor neuron death caudal ...
KEY FINDING: C2Hx had no detectable impact on phrenic motor neuron survival with either subacute (2-weeks) or chronic (8-weeks) spinal injury.
Glia, 2021 • December 1, 2021
The study investigates the expression and function of glutamine synthetase (GS) in oligodendrocytes (OL) of the mouse and human spinal cord. The researchers found that GS is expressed in mature OL but...
KEY FINDING: GS is expressed in myelinating oligodendrocytes (OL) but not oligodendrocyte progenitor cells in the mouse and human ventral spinal cord.
Orthopaedic Surgery, 2021 • December 1, 2021
This study compared early versus delayed surgery for acute spinal cord injuries in Beijing, finding that early surgery may lead to better neurological recovery. Early surgery was associated with incre...
KEY FINDING: Patients who underwent early surgery had a significantly higher chance of at least a two-grade improvement on the American Spinal Injury Association Impairment Scale (AIS) compared to those with delayed surgery.