Browse the latest research summaries in the field of cardiovascular science for spinal cord injury patients and caregivers.
Showing 221-230 of 309 results
Heliyon, 2023 • October 27, 2023
This study evaluated the regulatory effect of Tetramethylpyrazine (TMP) on the spinal cord injury (SCI) rat model and clarified the neuroprotective mechanism of TMP on SCI. The study results presented...
KEY FINDING: TMP promotes angiogenesis, nerve regeneration, and repair of nerve defects in SCI rats.
The Journal of Spinal Cord Medicine, 2019 • July 1, 2019
This study investigated the influence of sex on adipose tissue distribution and its relationship with inflammatory adipokines and cardiometabolic profiles in individuals with motor complete spinal cor...
KEY FINDING: Male participants with SCI had significantly greater visceral adipose tissue (VAT) volume and VAT:SAT ratio compared to females.
Exp Neurol, 2016 • October 1, 2016
This study investigates the roles of MMP-2 and MMP-9 in angiogenesis and vascular stability following spinal cord injury (SCI) in mice. It compares MMP-2 knockout (KO) mice with wildtype (WT) litterma...
KEY FINDING: MMP-2 deficiency resulted in reduced endothelial cell division within the lesioned epicenter.
Medicine, 2015 • October 1, 2015
This retrospective cohort study, using data from Taiwan's National Health Insurance Database, investigated the relationship between spinal cord injury (SCI) and the risk of peripheral arterial disease...
KEY FINDING: Patients with SCI have a significantly higher risk of developing PAD compared to those without SCI (HR = 1.37; 95% CI = 1.22–1.53).
AGING, 2023 • February 1, 2023
This study investigated the impact of short-term platelet depletion on Alzheimer's disease neuropathology in APP-PS1 mice. The researchers found that platelet depletion in female APP-PS1 mice augmente...
KEY FINDING: Platelet depletion in APP-PS1 female mice shifted amyloid plaque size distribution towards bigger plaques and increased neuritic dystrophy in the hippocampus.
BMC Cardiovascular Disorders, 2025 • January 21, 2025
This retrospective study of 447 ATAAD patients undergoing urgent TAR and FET found that MI-HCA was associated with shorter CPB time and reduced blood transfusion needs. MI-HCA patients had better post...
KEY FINDING: MI-HCA was associated with a shorter CPB time, and reduced blood transfusion requirements.
Nat Med, 2012 • November 1, 2012
Angiogenesis is a key feature of central nervous system injury. A neovessel-derived signal mediated by prostacyclin triggers axonal sprouting and functional recovery in a mouse model of inflammatory s...
KEY FINDING: Neovessels are formed in perilesional tissue in both inflammatory and traumatic spinal cord injury3,4. In this issue of Nature Medicine, Muramatsu et al.5 use a highly targeted inflammatory injury to the thoracic spinal cord that damages descending corticospinal tract (CST) projections from the brain to model some aspects of human multiple sclerosis.
Diagnostics, 2022 • October 22, 2022
The study analyzed 189 convalescent plasma (CP) donations from 66 donors to determine the optimal time span for CP donation based on anti-SARS-CoV-2 anti-S IgG antibody levels. It found a significant ...
KEY FINDING: There is a significant correlation between semi-quantitative SARS-CoV-2 IgG ratio values and in vitro antibody functionality.
J Spinal Cord Med, 2006 • January 1, 2006
Asymptomatic deep venous thrombosis (DVT) has been reported in 60% to 100% of persons with spinal cord injury (SCI). Retrievable VCFs are a safe, feasible option for secondary prophylaxis of VTE in pa...
KEY FINDING: VCFs are effective at preventing pulmonary embolism from lower-extremity DVT, with a success rate of about 98%.
Neural Regeneration Research, 2023 • November 9, 2022
This study demonstrates that aging impairs neurological recovery and angiogenesis following spinal cord injury (SCI) in mice. Metformin, a common drug for type 2 diabetes, was found to promote angioge...
KEY FINDING: Aging hinders neurological function recovery and blood vessel formation in the spinal cord after injury.