Endocrinology Research
Browse the latest research summaries in the field of endocrinology for spinal cord injury patients and caregivers.
Showing 141-150 of 217 results
Weight gain following spinal cord injury: a pilot study
The Journal of Spinal Cord Medicine, 2011 • January 1, 2011
This retrospective chart review aimed to define the temporal course of weight gain in persons with new SCI and identify predictors of weight gain. The study found a significant increase in BMI after n...
KEY FINDING: Mean BMI increased significantly after SCI, with the greatest increase occurring during the first year post-injury.
Neurogenic obesity and systemic inflammation following spinal cord injury: A review
The Journal of Spinal Cord Medicine, 2018 • January 1, 2018
SCI results in reduced metabolism, leading to adipose tissue accumulation and neurogenic obesity. Neurogenic obesity causes chronic, systemic inflammation through the overexpression of proinflammatory...
KEY FINDING: Obesity in SCI leads to chronic inflammation due to proinflammatory adipokines released from excess adipose tissue.
The influence of level of spinal cord injury on adipose tissue and its relationship to inflammatory adipokines and cardiometabolic profiles
The Journal of Spinal Cord Medicine, 2018 • July 1, 2018
The study examined the effect of level of spinal cord injury (LOI) on adipose tissue, proinflammatory adipokines, and cardiometabolic profiles in individuals with motor complete SCI. Results indicated...
KEY FINDING: The study found that the level of injury did not significantly influence the distribution of adipose tissue.
Body composition changes with testosterone replacement therapy following spinal cord injury and aging: A mini review
The Journal of Spinal Cord Medicine, 2018 • January 1, 2018
This mini-review presents evidence for TRT as a potential strategy to aid in the management of body composition changes and to improve metabolism in persons with SCI. In the absence of adequate studie...
KEY FINDING: Transdermal TRT can increase LBM and reduce FM over 3–36 months, relative to placebo, in hypogonadal elderly men and to a lesser extent in men with SCI.
Higher dietary intake of vitamin D may influence total cholesterol and carbohydrate profile independent of body composition in men with Chronic Spinal Cord Injury
The Journal of Spinal Cord Medicine, 2018 • July 1, 2018
This study aimed to determine the effects of dietary vitamin D intake on insulin sensitivity (Si), glucose effectiveness (Sg), and lipid profile in individuals with spinal cord injury (SCI). The key f...
KEY FINDING: Individuals with higher vitamin D intake had significantly lower total cholesterol levels compared to those with lower intake (P = 0.035).
Relationship Between Gonadal Function and Cardiometabolic Risk in Young Men with Chronic Spinal Cord Injury
PM R, 2018 • April 1, 2018
This study examined the relationship between testosterone levels and cardiometabolic risk factors in young men with chronic spinal cord injury (SCI). It found that low testosterone levels are associat...
KEY FINDING: Men with low free testosterone had significantly higher Framingham Risk Scores, indicating a greater risk of cardiovascular events.
Plasma leptin and reduced FEV1 and FVC in Chronic Spinal Cord Injury
PM R, 2018 • March 1, 2018
This study investigated the associations between plasma leptin and adiponectin levels and pulmonary function in individuals with chronic spinal cord injury (SCI). The results showed a significant inve...
KEY FINDING: There was a statistically significant inverse relationship between plasma leptin with FEV1 and FVC.
Management of obesity after spinal cord injury: a systematic review
The Journal of Spinal Cord Medicine, 2017 • September 1, 2017
This systematic review aimed to identify and compare the effectiveness of various interventions for managing obesity in individuals with chronic SCI. The review found that bariatric surgery produced t...
KEY FINDING: Bariatric surgery resulted in the greatest and most sustained weight loss and BMI correction in individuals with chronic SCI.
Liver Adiposity and Metabolic Profile in Individuals with Chronic Spinal Cord Injury
BioMed Research International, 2017 • August 30, 2017
This study investigated the relationship between liver adiposity, measured by MRI, and metabolic profile in men with chronic spinal cord injury (SCI). The results showed that increased liver fat was a...
KEY FINDING: Fat signal fraction (FSF) in the liver was positively related to triglycerides (TG), non-HDL-C, fasting glucose, and HbA1c, indicating a link between liver fat and poorer lipid and glucose control.
Daily parathyroid hormone administration enhances bone turnover and preserves bone structure after severe immobilization-induced bone loss
Physiol Rep, 2017 • September 1, 2017
This study demonstrates that severe immobilization following SCI leads to significant bone loss and reduced bone turnover in mice. Daily administration of PTH protects against SCI-induced bone loss by...
KEY FINDING: SCI-vehicle animals exhibited a marked decrease in proximal tibial fractional trabecular bone volume and trabecular thickness compared to the control sham-vehicle group.