Browse the latest research summaries in the field of endocrinology for spinal cord injury patients and caregivers.
Showing 61-70 of 211 results
PLoS ONE, 2020 • July 29, 2020
The major finding of this study was that applying SCI specific WC cutoff point (> 86.5 cm) improves the diagnostic ability of the existing indices and criteria to accurately capture those at risk of d...
KEY FINDING: Using SCI specific WC cutoff point of 86.5 cm, 36% of participants were classified as obese compared to only 3% when using WC of 102 cm.
Top Spinal Cord Inj Rehabil, 2020 • July 1, 2020
Individuals with chronic spinal cord injury (SCI) are predisposed to accelerated atherogenesis, dyslipidemia, and glycemic dysregulation, although not enough is known about the etiologies or clinical ...
KEY FINDING: People with chronic SCI are at increased risk for atherogenesis and ischemic heart disease.
Top Spinal Cord Inj Rehabil, 2021 • January 1, 2021
Physiological changes in adipose tissue following SCI should be characterized as neurogenic obesity due to an obligatory sarcopenia, neurogenic osteoporosis, neurogenic anabolic deficiency, sympatheti...
KEY FINDING: Individuals with SCI have altered energy balance due to sarcopenia, neurogenic osteoporosis, neurogenic anabolic deficiency, sympathetic dysfunction, and blunted satiety.
Top Spinal Cord Inj Rehabil, 2021 • January 1, 2021
The study compares body composition assessment techniques in individuals with SCI to the 4-compartment (4C) model, the criterion standard for measuring body fat. A regression equation incorporating ag...
KEY FINDING: A regression equation using age, sex, weight, and abdominal skinfold thickness can estimate body fat with reasonable accuracy in SCI patients.
Top Spinal Cord Inj Rehabil, 2021 • January 1, 2021
Spinal cord injury (SCI) results in dramatic changes in body composition, with lean mass decreasing and fat mass increasing in specific regions that have important cardiometabolic implications. The re...
KEY FINDING: SCI leads to regionally specific changes in body composition, with increased adiposity around the viscera, skeletal muscle, and bone marrow.
Top Spinal Cord Inj Rehabil, 2021 • January 1, 2021
A traumatic injury to the spinal cord causes an immediate cascade of inflammatory responses that, among other things, can initiate hypersensitivity within nociceptive pathways leading to chronic neuro...
KEY FINDING: Higher BMI is associated with greater pain severity in persons with chronic SCI, irrespective of the type of pain.
Top Spinal Cord Inj Rehabil, 2021 • January 1, 2021
Obesity is a common cardiometabolic risk factor in SCI, and exercise is a primary treatment strategy. However, tailoring exercise to manage obesity in SCI requires careful consideration of the reduced...
KEY FINDING: SCI leads to reduced muscle mass and decreased oxidative capacity, limiting the effectiveness of exercise in creating a calorie deficit.
International Journal of General Medicine, 2021 • March 16, 2021
This study evaluated bone mineral density (BMD) changes at the distal femur (DF) and proximal tibia (PT) in spinal cord injury (SCI) patients during the first year after injury. The BMDs at the DF and...
KEY FINDING: BMD at the DF, PT, and hip were significantly lower in SCI patients than in controls.
Frontiers in Endocrinology, 2021 • May 11, 2021
This study investigated the impact of spinal cord injury (SCI) on FGF21 and adiponectin signaling in mice, focusing on liver, adipose tissue, and skeletal muscle. The findings indicated that SCI reduc...
KEY FINDING: SCI reduced serum FGF21 levels and hepatic FGF21 expression, as well as b-klotho and FGF receptor-1 (FGFR1) mRNA expression in adipose tissue.
J. Funct. Morphol. Kinesiol., 2022 • October 17, 2022
This study investigates the effect of low force electrically induced exercise (LFE) on postprandial glycemic markers in individuals with spinal cord injury (SCI). The results indicate that LFE attenua...
KEY FINDING: People with SCI had higher fasting insulin, lactate, C-reactive protein, uric acid, alkaline phosphatase, and low-density lipoprotein compared to the non-SCI population.