Browse the latest research summaries in the field of immunology for spinal cord injury patients and caregivers.
Showing 91-100 of 620 results
Journal of Neurology, 2022 • May 24, 2022
This study analyzed T lymphocyte subpopulations in PD patients and healthy controls, finding significant differences in naïve CD8+ T cells and late-differentiated CD4+ T cells. These T-cell changes we...
KEY FINDING: PD patients exhibited decreased naïve CD8+ T cells and increased late-differentiated CD4+ T cells compared to healthy controls.
European Journal of Trauma and Emergency Surgery, 2022 • June 3, 2022
This study compared patients with pyogenic spinal infections with and without spinal cord injury (SCI), analyzing diagnostics, therapy, and outcomes. The study found that while overall survival was si...
KEY FINDING: The presence of endocarditis was significantly higher in the noSCI group compared to the SCI group (9% vs. 0%; p=0.03).
Med, 2022 • August 12, 2022
This study investigated the impact of heterologous prime-boost COVID-19 vaccination schedules on antibody response against SARS-CoV-2 variants in healthcare workers. The researchers found that the ord...
KEY FINDING: Strongest serum neutralization activity against the SARS-CoV-2 variant B.1.617.2 among recipients of heterologous BBIBP-CorV/CoronaVac and WIBP-CorV/CoronaVac.
Journal of Neuroinflammation, 2022 • June 5, 2022
This study investigates the role of Apelin in treating spinal cord injury (SCI) by reducing neuroinflammation and promoting neural stem cell (NSC) proliferation and differentiation. The researchers fo...
KEY FINDING: Apelin expression decreases after SCI and then increases later, suggesting its involvement in both injury and repair.
Frontiers in Immunology, 2022 • June 28, 2022
This study performed a detailed immune profiling of SCI patients in the (sub)acute and chronic disease phase using high-dimensional flow cytometry. Changes in the frequencies of circulating immune cel...
KEY FINDING: Total and CD4+ T cell frequencies were increased in cSCI patients.
International Journal of Exercise Science, 2022 • January 1, 2022
This study examined the impact of a 30-minute submaximal aerobic exercise bout on circulating leukocyte populations in individuals with SCI, finding increases in lymphocyte subsets. The exercise-induc...
KEY FINDING: Acute exercise significantly increased total lymphocytes, CD4+ T helper cells, CD8+ T cytotoxic cells, CD3-/CD56+ NK and CD3+/CD56+ NKT cells.
The Journal of Spinal Cord Medicine, 2020 • May 1, 2020
The study prospectively evaluated urodynamic changes in individuals with SCI practicing CIC to understand long-term complications despite CIC and compare the urodynamic bladder profile of overactive d...
KEY FINDING: Cystometric capacity and compliance decreased significantly over time, despite regular CIC and antimuscarinic medication use.
JOURNAL OF NEUROTRAUMA, 2019 • December 15, 2019
The study assessed factors associated with circulating BAFF in non-ambulatory males with chronic SCI, finding that active smokers had significantly greater BAFF levels than former/nonsmokers. The rese...
KEY FINDING: Active smokers had significantly greater BAFF levels than former/nonsmokers (871 pg/mL vs. 665 pg/ml, p = 0.002).
Spinal Cord Series and Cases, 2019 • September 1, 2019
This case report presents the successful management of chronic prostatitis in a spinal cord injury (SCI) male through transurethral prostatectomy (TURP) after conservative treatments failed. The patie...
KEY FINDING: The patient, a 52-year-old male with T12 AIS A SCI, experienced resolution of recurrent UTIs and urethral discharge after undergoing TURP.
Scientific Reports, 2019 • October 15, 2019
This study investigated the roles of activated microglia and infiltrating macrophages in neuropathic pain (NeP) associated with chronic progressive spinal cord compression using a mouse model. The mai...
KEY FINDING: The severity of spinal cord compression correlated with the proportion of activated microglia and hematogenous macrophages in the spinal cord.