Browse the latest research summaries in the field of immunology for spinal cord injury patients and caregivers.
Showing 601-610 of 620 results
The Journal of Spinal Cord Medicine, 2019 • July 1, 2019
This study prospectively assessed the usefulness of classical homeopathy for preventing urinary tract infections (UTI) in patients with neurogenic lower urinary tract dysfunction (NLUTD) due to spinal...
KEY FINDING: Adjunctive homeopathic treatment led to a significant decrease in the number of self-reported UTI in the homeopathy group, whereas it remained unchanged in the control group.
Spinal Cord Series and Cases, 2016 • September 15, 2016
This case report highlights the diagnostic challenges in HIV-vacuolar myelopathy, emphasizing that a negative MRI scan does not exclude the condition. The importance of assessing both peripheral and c...
KEY FINDING: A negative or unspecific MRI scan does not rule out HIV-related myelopathy in HIV-positive patients with myelopathy symptoms.
VIEW, 2022 • March 2, 2022
This study reveals that acidosis-related pH promotes SARS-CoV-2 infection by increasing ACE2 expression on the cell membrane, suggesting a positive feedback loop where SARS-CoV-2 infection-induced aci...
KEY FINDING: Acidosis-related pH (6.8) increases the expression of SARS-CoV-2 receptor ACE2 on the cell membrane.
Journal of Nanobiotechnology, 2024 • May 28, 2024
This study introduces a nanoenzyme-based scaffold (NS@COP) designed to address key challenges in spinal cord injury (SCI) repair, including inflammation, mitochondrial dysfunction, and glial scar form...
KEY FINDING: NS@COP restores the responsiveness of pro-inflammatory macrophages to CGRP by upregulating RAMP1, promoting an anti-inflammatory M2 phenotype.
J Spinal Cord Med, 2006 • January 1, 2006
This study evaluated the incidence and etiology for fever following acute SCI, and to evaluate associated risk factors (such as the level and completeness of injury) that may predispose to fever. This...
KEY FINDING: The incidence of fever was 60.4% and 50% in acute care and rehabilitation, respectively.
Journal of Clinical Laboratory Analysis, 2015 • January 1, 2015
This retrospective study compared three different test systems (ELISA, solid-phase assay, and LCT) for detecting platelet antibodies in 1,234 patient samples. The results showed significant divergence...
KEY FINDING: Platelet antibodies were detected in 29.7% of the 1,234 samples tested.
Frontiers in Surgery, 2023 • September 11, 2023
Failed fracture healing remains a significant complication, and ongoing research aims to improve understanding of contributing factors at local and systemic levels. The immune system's role in bone he...
KEY FINDING: Interferon-gamma (IFN-y) signaling plays a key role in orchestrating immunological functions and serves an anabolic function in osseous biology, leading to osteoblastic activation.
Journal of Neuroinflammation, 2023 • October 10, 2023
This study reveals two novel normally occurring CD47-dependent mechanisms that impede myelin debris clearance by acting as a cell surface receptor. First, CD47 on Schwann cells inhibits myelin disrupt...
KEY FINDING: Myelin debris clearance, axon regeneration, and function recovery were all faster in CD47−/− mice than in wild type mice.
Neural Regeneration Research, 2025 • July 29, 2024
This review examines the therapeutic strategies targeting the C–C motif chemokine ligand 2/C–C motif chemokine receptor 2 axis, along with the regenerative and repair mechanisms linking the axis to sp...
KEY FINDING: The CCL2/CCR2 axis recruits immune cells to the injury site, stimulating microglia and macrophages, which exacerbates the inflammatory response and nerve damage, worsening SCI.
Computational and Mathematical Methods in Medicine, 2022 • October 1, 2022
This study explores the role of TRIM28 in LIHC, finding that its expression is upregulated in tumors and associated with poor prognosis. The research identifies correlations between TRIM28 expression ...
KEY FINDING: High TRIM28 expression level was associated with T classification, pathologic stage, histologic grade, and serum AFP levels.