Neurology Research

KEY FINDING: Fulfilment of individual process performance measures (PPMs) was associated with adjusted hazard rate ratios of death between 0.76 and 0.96.

KEY FINDING: OECs enhanced total neurite outgrowth of cortical neurons in a scar-like environment by 60%.

KEY FINDING: More than 70% of participants rated improvements in arm/hand function as “very important” to regain.

KEY FINDING: Tau inhibition after spinal cord injury down-regulated the levels of inflammatory mediators, including tumor necrosis factor-α, interleukin-6 and interleukin-1β.

KEY FINDING: Microglia are an important component of the protective scar that forms after SCI. Microglia form a dense cellular interface between reactive astrocytes and infiltrating monocyte-derived macrophages at the border of the lesion post-SCI.

KEY FINDING: Astrocytes can support axon regeneration under experimental conditions that enhance axons’ intrinsic capacity to grow, such as through Pten gene deletion.

KEY FINDING: Inhibition of 2-AG hydrolysis reduces CSPGs accumulation and astrogliosis around demyelinated lesions in the spinal cord of Theiler’s murine encephalomyelitis virus-infected mice.

KEY FINDING: The root mean squared (RMS) error between actual frame coordinates and software-coordinates, both acquired using the test phantom, was 1.09 ± 0.20 mm.

KEY FINDING: Polysaccharide-based DDSs, especially those using chitosan, alginate, and agarose, show promise in treating SCI by promoting axonal regeneration and reducing inflammation.

KEY FINDING: Neural progenitor cell (NPC) reactivity increased in the central canal at all levels of the spinal cord after thoracic SCI.