Neurology Research

KEY FINDING: The study identified that essential tremor could be elicited by the central oscillation signals through the multisynaptic corticospinal pathway involving the propriospinal neuron network.

KEY FINDING: The combination of rosiglitazone and forskolin resulted in better locomotor recovery in SD rats after SCI compared to either treatment alone.

KEY FINDING: A preconditioning crush injury to the tibial nerve significantly attenuated mechanical allodynia and thermal hyperalgesia following partial sciatic nerve ligation (PSNL).

KEY FINDING: Zebrafish spinal cord regeneration involves a brief inflammatory response, macrophage activity to clear myelin debris, minimal cell loss, extensive neurogenesis, and a permissive environment for axonal regrowth.

KEY FINDING: STAT3 translocates to both the nucleus and mitochondria in mature CNS neurons upon cytokine stimulation, suggesting distinct roles in different cellular compartments.

KEY FINDING: The extent of axonal destruction during the acute phase of idiopathic polyneuritis is a key determinant of long-term recovery.

KEY FINDING: IL-6 induces SOCS3 expression in NS-1 cells, leading to STAT3 activation, and SOCS3 negatively regulates STAT3 activation, inhibiting IL-6-induced neuritic outgrowth in vitro.

KEY FINDING: A single CM administration to the cerebellum had a mild effect on the balance and motor deficits of SCA3/MJD mice.

KEY FINDING: Eliminating FnEDA did not reduce the acute fibrotic response but markedly diminished chronic fibrotic scarring after SCI.

KEY FINDING: Spinal cord capillaries, especially in the anterior horn, have fewer pericytes compared to brain capillaries in wild-type mice.