Browse the latest research summaries in the field of neurology for spinal cord injury patients and caregivers.
Showing 5,111-5,120 of 5,253 results
PLoS ONE, 2016 • July 22, 2016
This study investigated the serum levels of IGF-1 in patients after traumatic spinal cord injury over a three-month period, finding distinct patterns in the expression of IGF-1 regardless of the degre...
KEY FINDING: IGF-1 serum levels were significantly different from initial measurements at four, nine hours, seven, 14 days after injury as well as one, two and three months after injury.
Brain Sci, 2021 • November 30, 2021
The study used RNA-sequencing to identify differentially expressed genes in fetal spinal cords from rats with retinoic acid-induced spina bifida at E15, E17, and E20. The results suggest common alterat...
KEY FINDING: The study found approximately 3000, 1000, and 300 genes were differentially expressed at E15, E17, and E20, respectively, compared to control groups.
Heliyon, 2018 • January 24, 2018
This systematic review examined the effect of dance interventions on balance, gait, and functional mobility in adults with neurological conditions other than Parkinson's disease. Nine studies were inc...
KEY FINDING: Dance interventions can lead to significant changes in spatiotemporal gait parameters, Berg Balance Scale scores, Timed Up and Go test, and six-minute walk test scores.
Thorac Cardiovasc Surg, 2025 • June 11, 2024
Deep hypothermia helps protect the spinal cord, but is invasive. The motor evoked potential disappeared during aortic clamping in nine patients. Six patients recovered completely from aortic clamping ...
KEY FINDING: The motor evoked potential disappeared during aortic clamping in nine patients.
The Journal of Neuroscience, 2002 • August 15, 2002
This study investigates the potential of olfactory mucosa (OM) transplantation to improve facial nerve regeneration in rats after nerve transection. The findings indicate that OM transplantation reduc...
KEY FINDING: OM transplantation improved vibrissae movement by up to 80% of control values, demonstrating enhanced motor performance.
Molecular Medicine, 2022 • August 3, 2022
The study investigates the therapeutic potential of modulating neuronal activity in sensory and motor neurons, using opto- and chemogenetic stimulation, to regulate axonal growth after injury. Results...
KEY FINDING: Optogenetic stimulation of DRG neurons increases axonal growth in vitro.
BMJ Open, 2017 • July 7, 2017
This protocol outlines a systematic review to study cognitive function in adults following CNS trauma (TBI, SCI). The review will identify the course of cognitive status, prognostic factors, and summa...
KEY FINDING: The systematic review aims to document the course of cognitive status (decline, improvement, stability, fluctuations, etc) in patients with CNS trauma as time since injury progresses.
Frontiers in Molecular Neuroscience, 2022 • September 7, 2022
This review focuses on the unique advantages of using zebrafish larvae as a model for studying spinal cord regeneration, emphasizing their optical transparency, simple anatomy, and complex locomotor b...
KEY FINDING: Spinal cord regeneration in zebrafish larvae is distinct from development, with injury-dependent responses such as immune cell infiltration and glial bridge formation.
Neural Regeneration Research, 2016 • July 1, 2016
The letter discusses a case report where a neural bypass system was used to restore hand functions in a person with tetraplegia. Micro-recording electrode arrays were implanted in the motor cortex to ...
KEY FINDING: The participant was able to perform six hand movements and daily functional tasks using neuromuscular electrical stimulation after the spinal cord injury was bypassed.
Exp Neurol, 2017 • January 1, 2017
Stroke triggers axonal sprouting in areas connected to the damage, initiating within the first week and involving the growth factor GDF10. This process involves a molecular growth program with coordin...
KEY FINDING: Post-stroke axonal sprouting occurs in mice, rats, primates and humans, suggesting it's a conserved response to brain injury.