Browse the latest research summaries in the field of orthopedics for spinal cord injury patients and caregivers.
Showing 331-340 of 352 results
BMC Musculoskeletal Disorders, 2022 • September 6, 2022
The study evaluated cartilage measurements using T2 mapping and R2* sequences in monkeys with normal and reduced knee ROM to determine which sequence is better at detecting microstructural cartilage c...
KEY FINDING: MRI-R2* sequence is superior to T2 mapping in the detection of microstructural cartilage changes in knees with limited ROM.
J. Clin. Med., 2023 • January 2, 2023
The study classified new bone formation in OPLL into plateau-shaped and hill-shaped patterns and investigated related factors, including serum hs-CRP levels and SI joint ankylosis. The research found ...
KEY FINDING: The plateau shape of OPLL was more common in vertebral segments, while the hill shape was predominant in intervertebral regions.
Neuroepidemiology, 2009 • November 8, 2008
This study examined both short- and long-term mortality in a 2-year cohort of veterans with preexisting neurological disorders and subsequent LE amputation in a large integrated US health system. Almo...
KEY FINDING: 43.3% of the 4,720 patients had neurological disorders documented prior to amputation.
J Spinal Cord Med, 2006 • January 1, 2006
This case report describes an unusual presentation of neuroarthropathy in the wrist of an individual with paraplegia. Neuroarthropathy typically affects weight-bearing joints due to repetitive trauma ...
KEY FINDING: A 42-year-old man with a 30-year history of paraplegia developed nonpainful swelling in his wrist, which had decreased sensation since his initial spinal cord injury.
Rev Bras Ortop, 2016 • February 2, 2016
The study evaluated the effect of complete absence of muscle contractions on normal human cartilage in the presence of joint motion in patients with complete spinal cord injuries. Patients underwent M...
KEY FINDING: Absence of muscle contractions seems deleterious to normal human knee cartilage.
Heliyon, 2022 • October 13, 2022
This study investigates the dynamics of cartilage-derived stem/progenitor cells (CSPCs) in osteoarthritis (OA) progression using single-cell transcriptomic data. The research reveals that CSPC heterog...
KEY FINDING: CSPCs exhibit significant heterogeneity that is closely associated with the progression of OA, indicating that the characteristics of CSPCs change during OA progression.
Journal of Orthopaedic Translation, 2024 • August 22, 2024
This review comprehensively examines the complex relationship between oxidative stress, mitochondrial dysfunction, and IVDD, highlighting potential therapeutic targets and concepts for future research...
KEY FINDING: Excessive ROS causes oxidative damage to DNA, proteins, and lipids within IVD cells, disrupting normal cell signaling and regulation pathways.
J Spinal Cord Med, 2008 • January 1, 2008
This study aimed to determine the effect of respiratory resistance training (RRT) with a concurrent flow respiratory (CFR) device on respiratory function and aerobic power in wheelchair athletes. The ...
KEY FINDING: RRT with a CFR device significantly improved maximal inspiratory pressure (MIP) in wheelchair athletes.
Frontiers in Bioengineering and Biotechnology, 2021 • November 30, 2021
The study aimed to enhance the biological performance of 3D-printed Ti6Al4V implants by modifying their surface with a polydopamine (PDA) coating. In vitro results showed that the PDA coating improved...
KEY FINDING: PDA coating enhanced the hydrophilicity of 3D-printed Ti6Al4V implants.
International Journal of Spine Surgery, 2022 • October 12, 2022
This systematic review summarizes the existing literature regarding the use of amniotic membrane preparations, treatment regimens, and indications within spinal surgery. The review of reported studies...
KEY FINDING: Amnion products show promising effects in reducing epidural adhesions and scar tissue after spine surgery.