Pain Management Research

KEY FINDING: A 30-year-old male with a T12 AIS B incomplete spinal cord injury secondary to multiple GSW experienced severe bilateral lower extremity dysesthesias and muscle spasms.

KEY FINDING: Neuropathic pain decreased immediately post-exercise for both tetraplegics (−60%) and paraplegics (−16%).

KEY FINDING: Dry needling immediately reduced spasticity in both upper and lower limbs, as measured by the modified Ashworth Scale.

KEY FINDING: MCAS exit latencies differed significantly between Burst SCS and Tonic SCS at 4 mm and 5 mm probe heights, indicating differential effects on cognitive-motivational aspects of pain.

KEY FINDING: A 37-year-old male with idiopathic TM and chronic neuropathic pain experienced 70% pain improvement during a SCS trial.

KEY FINDING: Provider adherence for most outcomes exceeded 70% completion within acceptable timeframes, with improvements found for all outcomes as compared to the retrospective cohort.

KEY FINDING: A higher proportion of participants reported a marked change in average pain intensity from baseline to 8 and 12 weeks post-BoNTA vs. post-placebo (33% vs. 0%).

KEY FINDING: The severity of spinal cord compression correlated with the proportion of activated microglia and hematogenous macrophages in the spinal cord.

KEY FINDING: Twelve participants regulated their brainwaves in a frequency specific manner and were most successful upregulating the alpha band power.

KEY FINDING: SCI-induced hypersensitivities to mechanical and thermal stimulation were relieved in plt mice compared with wild-type mice.