Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 161-170 of 555 results
JOURNAL OF NEUROTRAUMA, 2020 • August 1, 2020
This study investigated the effects of FTY720 on neuropathic pain in a rat model of spinal cord injury (SCI). FTY720, a sphingosine-1-phosphate receptor agonist, was administered to female rats 24 hou...
KEY FINDING: FTY720 significantly attenuated post-traumatic neuropathic pain in a rat model of spinal cord injury.
Medicine, 2019 • December 6, 2019
This case report describes a 50-year-old woman who developed acute cervical myelopathy with quadriparesis following a cervical TFESI. MRI revealed spinal cord damage, and the patient was treated with ...
KEY FINDING: Cervical TFESI can lead to spinal cord injury despite careful fluoroscopic guidance.
Journal of Exercise Rehabilitation, 2019 • December 1, 2019
This study aimed to determine the most effective core stability exercise position and technique (drawing-in vs. bracing) for activating the transverse abdominis (TrA) muscle. We aimed to compare the a...
KEY FINDING: Abdominal bracing in the bridge position resulted in the highest activation of the transverse abdominis muscle compared to other positions and the drawing-in technique. AB in the bridge position showed the highest activation of TrA.
BMC Neurology, 2020 • February 12, 2020
This case report details a 50-year-old man who developed severe bilateral occipital pain following a fall that resulted in a small central cervical spinal cord injury (SCI) at the C2 level. The patien...
KEY FINDING: The patient experienced severe bilateral occipital pain (at-level neuropathic pain) due to a small central cervical SCI, which is an unusual presentation.
Neuromodulation, 2021 • January 1, 2021
This study investigates the impact of spinal cord stimulation (SCS) on protein expression in the spinal cord of rats with neuropathic pain. The results showed that SCS leads to a significant improveme...
KEY FINDING: SCS significantly improved mechanical sensitivity in animals with neuropathic pain after 48 hours of therapy.
Neural Plasticity, 2020 • March 10, 2020
This study investigated the reorganization of insular subregions in individuals suffering from neuropathic pain (NP) after incomplete spinal cord injury (ISCI) to disclose the underlying mechanism of ...
KEY FINDING: Compared to ISCI individuals without neuropathic pain, those with neuropathic pain showed increased functional connectivity between the left posterior insula and the right cerebellum VIIb and VIII, as well as Brodmann area 37.
Korean J Pain, 2020 • April 1, 2020
The study compared the effects of TENS, SCS, and MA on neuropathic, inflammatory, and non-inflammatory pain models in rats. TENS and SCS were effective in all three pain models, while MA was only effe...
KEY FINDING: TENS and SCS produce similar effects in neuropathic, inflammatory and non-inflammatory muscle pain models.
International Journal of Molecular Sciences, 2020 • March 30, 2020
This study evaluated the analgesic effects of spinal cord stimulation (SCS) on neuropathic pain following spared nerve injury (SNI) in rats, focusing on the role of microglial activation and neuronal ...
KEY FINDING: SCS and minocycline both reduced plantar mechanical hypersensitivity in rats after spared nerve injury (SNI), indicating a reduction in pain sensitivity.
Pain Research and Management, 2020 • April 10, 2020
This study investigates the effect of 2 Hz electroacupuncture (EA) on neuropathic pain in rats with spared nerve injury (SNI), focusing on the role of interferon regulatory factor 8 (IRF8) and CX3CRl ...
KEY FINDING: Spared nerve injury (SNI) significantly increased spinal IRF8 and CX3CRl mRNA and protein expression in rats.
The Journal of Neuroscience, 2020 • May 27, 2020
This study used intravital imaging to profile dendritic spine dynamics in the superficial dorsal horn of mice before and after peripheral nerve injury, providing insights into the structural changes a...
KEY FINDING: Peripheral nerve injury leads to increased fluctuations in the length and width of dendritic spines in the dorsal horn neurons.