Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 241-250 of 555 results
International Journal of Surgery Case Reports, 2020 • October 25, 2020
This case report describes a rare instance of cauda equina syndrome following a caudal epidural sacral injection in a 63-year-old male with severe lumbar spinal stenosis. The patient presented with mo...
KEY FINDING: Caudal epidural sacral injection in a patient with severe lumbar spinal stenosis resulted in cauda equina syndrome immediately after the procedure.
BMC Musculoskeletal Disorders, 2023 • February 15, 2023
This study explored the pain-inhibitory effects of neuromuscular electrical stimulation (NMES) compared to volitional contractions and noxious electrical stimulation (NxES) in healthy participants. Th...
KEY FINDING: Noxious electrical stimulation (NxES) produced higher pain ratings compared to neuromuscular electrical stimulation (NMES).
Molecular Pain, 2020 • January 1, 2020
This study investigated the effects of differential target multiplexed programming (DTMP) compared to low-rate (LR) and high-rate (HR) spinal cord stimulation (SCS) on neuropathic pain in rats. Behavi...
KEY FINDING: DTMP significantly reduced both mechanical and thermal hypersensitivity compared to low and high-rate SCS.
Brain, Behavior, & Immunity - Health, 2020 • July 25, 2020
This study investigated the impact of nerve injury on mood disorders and memory loss, examining the roles of cytokines, growth factors, and glial cells in the process. The researchers induced nerve in...
KEY FINDING: Nerve injury induces depressive-like and anxiety-like behaviors as well as impairment in short-term memory in mice.
Indian J Otolaryngol Head Neck Surg, 2022 • August 3, 2021
The study investigated SCM-VEMP and SETMP responses in patients with CMPS-D compared to a control group to assess saccular function and the etiology of dizziness. SCM-VEMP amplitudes were significantl...
KEY FINDING: The SCMVEMP response was absent in 4 of 15 patients with CMPS-D, and the mean response in the CMPS-D group was significantly lower than the control group.
Journal of International Medical Research, 2021 • May 1, 2021
This case report describes a patient who developed SCI after TPI in the left thoracolumbar paraspinal muscles. MRI and electrophysiological studies confirmed the presence of edema/inflammation in the ...
KEY FINDING: The patient experienced an electric shock sensation during the TPI procedure, followed by weakness and neuropathic pain in the left lower extremity.
Physiological Reports, 2019 • January 1, 2019
This study demonstrates that dendritic spine dysgenesis occurs in ventral horn motor neurons following burn injury, suggesting motor neuron synaptic plasticity. Romidepsin, a Pak1-inhibitor, restored ...
KEY FINDING: Second-degree burn injury significantly affects motor neuron structure within the spinal cord, specifically increasing dendritic spine density.
J. Clin. Med., 2023 • December 23, 2022
The study assessed TSPO expression as an indicator of microglial activation using (R)-[11C]PK11195 PET imaging in a rat SCI model. Clinical application of (R)-[11C]PK11195 PET/MRI in patients with NeP...
KEY FINDING: TSPO is mainly expressed in activated microglia in the injured spinal cord.
PM R, 2014 • August 1, 2014
This study examined the relationship between pain location and its impact on functioning in individuals with spinal cord injury (SCI) and chronic pain. The research aimed to determine if pain site and...
KEY FINDING: Pain extent and intensity are positively associated with pain interference (r = 0.33, P < .01), indicating that greater pain extent and intensity lead to more significant interference with daily activities.
The Journal of Spinal Cord Medicine, 2014 • January 1, 2014
This study evaluated the effectiveness of rTMS for treating intractable neuropathic pain in SCI patients. Seventeen participants were randomized into real and sham rTMS groups and received ten daily s...
KEY FINDING: Both real and sham rTMS significantly reduced pain scores (VAS) in patients with SCI and neuropathic pain.