Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 251-260 of 555 results
JOURNAL OF NEUROTRAUMA, 2016 • July 15, 2016
The study investigated the relationship between neuropathic pain symptoms, pain severity, and N-acetylaspartate (NAA) levels in brain areas involved in pain processing among individuals with subacute ...
KEY FINDING: Subjects with Moderate Neuropathic Pain had significantly lower insular NAA than the Low or no Neuropathic Pain group.
Neurorehabil Neural Repair, 2016 • August 1, 2016
The study determined if delaying exercise intervention until pain is detected would similarly ameliorate established SCI-induced pain. The results show that delaying exercise until allodynia develops ...
KEY FINDING: Exercise therapy initiated at early stages of allodynia is ineffective at attenuating neuropathic pain.
The Journal of Spinal Cord Medicine, 2017 • May 1, 2017
A consensus-building workshop in 2006 aimed to develop a research agenda for SCI-related chronic pain, involving 39 stakeholders and using a modified Delphi approach to identify top research prioritie...
KEY FINDING: The top five pain research priorities identified were pain management and treatment, measurement tools, health services policy and advocacy, knowledge transfer, and mechanisms of pain.
The Journal of Spinal Cord Medicine, 2017 • May 1, 2017
The study explored the relationship between pain and mood during spinal cord injury rehabilitation, finding significant correlations between the two. Improvements in pain were associated with improvem...
KEY FINDING: Significant improvements were observed in both pain and mood from the initial assessment (NAC1) to the pre-discharge assessment (NAC2).
The Journal of Spinal Cord Medicine, 2017 • July 1, 2017
This pilot study investigated the effects of Battlefield Acupuncture (BFA) on neuropathic pain in individuals with spinal cord injury (SCI). The study found that participants who received BFA reported...
KEY FINDING: The BFA group reported significantly more pain reduction than the delayed entry group (average change in NRS at eight weeks –2.92 ± 2.11 vs. −1.13 ± 2.14, P = 0.065).
The Journal of Spinal Cord Medicine, 2016 • January 1, 2016
The study examined the relationship between neuropathic and nociceptive pain, pain interference, and quality of life (QoL) in individuals with spinal cord injury (SCI) participating in an antidepressa...
KEY FINDING: Lower baseline nociceptive pain interference was associated with higher satisfaction with life and mental health-related QoL at 12 weeks.
Journal of Pain Research, 2014 • July 1, 2014
The study evaluated health care resource utilization (HRU) and costs for neuropathic pain (NeP) secondary to spinal cord injury (SCI) among Medicaid beneficiaries. Significantly higher HRU and total c...
KEY FINDING: Patients with SCI-NeP had significantly higher percentages of physician office visits, emergency department visits, SCI- and pain-related procedures, and outpatient prescription utilization compared to the SCI-only cohort.
Journal of Pain Research, 2014 • July 28, 2014
The study aimed to evaluate the long-term safety and tolerability of pregabalin in Japanese patients with central neuropathic pain over a 53-week period. The results indicated that pregabalin was gene...
KEY FINDING: A majority of patients (87.4%) experienced at least one treatment-related adverse event, most commonly somnolence, weight gain, dizziness, or peripheral edema.
Eur J Pain, 2015 • May 1, 2015
This study investigates the differential contributions of N-, L-, and P/Q-type voltage-gated calcium channels (VGCC) to behavioral hypersensitivity mediated by Cavα2δ1 dysregulation using a Cavα2δ1 ov...
KEY FINDING: N-type and L-type VGCC blockers (ω-conotoxin GVIA and nifedipine, respectively) significantly attenuated mechanical hypersensitivity in both the Cavα2δ1 overexpression (TG) and spinal nerve ligation (SNL) models.
Pain Med, 2014 • December 1, 2014
The study investigated whether baseline EEG-assessed brain oscillations predict response to neuromodulatory treatments for chronic pain in individuals with spinal cord injury. The key finding was that...
KEY FINDING: Higher presession theta activity was associated with greater pain reduction with hypnotic analgesia.