Browse the latest research summaries in the field of physiology for spinal cord injury patients and caregivers.
Showing 151-160 of 292 results
J Spinal Cord Med, 2009 • April 1, 2009
This study examined how different doses of baclofen, administered orally and intrathecally, affected spasticity and strength in a patient with an incomplete spinal cord injury. Both clinical and neuro...
KEY FINDING: Spasticity and strength changed as the baclofen dose was adjusted.
Clin Neurophysiol, 2009 • September 1, 2009
The study aimed to determine if upper limb effort could enhance maximal lower limb muscle activation in individuals with incomplete spinal cord injury during recumbent stepping. The results showed tha...
KEY FINDING: Upper limb effort did not increase lower limb muscle activation during active lower limb effort in individuals with incomplete spinal cord injury during recumbent stepping.
Exp Neurol, 2010 • March 1, 2010
This study assessed the chronic effects of low thoracic hemisection on the cough reflex in cats. The major finding is that expiratory motor drive to abdominal muscles is not significantly impaired dur...
KEY FINDING: Expiratory motor drive to abdominal muscles is not significantly impaired during cough in cats that are chronically hemisected in the lower thoracic spinal cord.
Respir Physiol Neurobiol, 2010 • May 31, 2010
This study investigated the feasibility of using high-frequency spinal cord stimulation (HF-SCS) to activate intercostal muscles for artificial ventilation in dogs with spinal cord injury. The results...
KEY FINDING: High-frequency spinal cord stimulation (HF-SCS) can maintain artificial ventilation by activating intercostal muscles alone in dogs with spinal cord injury and bilateral phrenicotomy.
Clin Neurophysiol, 2010 • October 1, 2010
Spinal motoneurons are the final neural output of the central nervous system (CNS) through which motor commands to peripheral muscles are communicated. The level of the monoaminergic drive from the br...
KEY FINDING: The motoneuronal PIC recovers after chronic SCI, restoring motoneuronal excitability and contributing to long-lasting reflexes and muscle spasms.
Spinal Cord, 2011 • March 1, 2011
The study neurophysiologically characterizes motor control recovery after SCI using multi-muscle sEMG recordings during reflex and volitional motor tasks. Results showed that SCI subjects had lower sE...
KEY FINDING: Overall, sEMG amplitudes were lower after SCI, and prime mover muscle voluntary recruitment was slower with disrupted multi-muscle patterns.
Eur Spine J, 2011 • January 9, 2011
This study quantified the Trömner sign using electrophysiological assessments to evaluate its diagnostic sensitivity for cervical spondylotic myelopathy (CSM). The results demonstrated that the quant...
KEY FINDING: Quantified electrophysiological tests showed positive Tro¨mner signs in all CSM patients, indicating high sensitivity.
BMC Neuroscience, 2013 • August 2, 2013
This study investigates the early molecular adaptations in rat soleus muscle after initiating isometric resistance exercise by electrical stimulation (ES) following spinal cord injury (SCI). ES increa...
KEY FINDING: ES increased expression of Hey1 and Pitx2, suggesting increased Notch and Wnt signaling, respectively, indicating involvement of these pathways in ES-induced muscle mass increases.
JOURNAL OF NEUROTRAUMA, 2012 • March 20, 2012
This study characterizes clonus in individuals with chronic cervical spinal cord injuries, focusing on muscle activation patterns and factors influencing clonus duration. Electromyographic activity wa...
KEY FINDING: Clonus frequency in the soleus muscle averaged 5.4 Hz and was slower when the reflex path was longer, indicating afferent input influences clonus.
Clin Neurophysiol, 2012 • March 1, 2012
This study demonstrated that mechanical oscillation of a single paralyzed limb segment modulates the amplitude of the H-reflex and influences the degree of post-activation depression in healthy and th...
KEY FINDING: Segmental vibration resulted in H-reflex depression in both SCI and healthy control groups.