Spinal Cord Injury Research

KEY FINDING: The full bowel preparation was tolerated by 91% of inpatients, indicating good tolerability of the regimen.

KEY FINDING: People with SCI were more likely to reside close to specialized SCI centers, indicating that access to specialized care influences residential choices.

KEY FINDING: Participants successfully captured various health data in their MyPHRs from providers, pharmacies, and activity trackers, demonstrating the potential for personalized healthcare after SCI.

KEY FINDING: Fasting plasma glucose levels decreased in the combined exercise group compared to the high-protein diet group.

KEY FINDING: One RCT provided Level 1 evidence that GM-1 ganglioside in combination with physical therapy improved motor scores, walking velocity and distance better than placebo and physical therapy in persons with incomplete SCI.

KEY FINDING: The training machine requires adjustments to be suitable for paraplegic subjects, including a platform to secure the wheelchair.

KEY FINDING: Droxidopa increased blood pressure levels in the patient, specifically a 10 mm Hg increase in systolic BP and 6 mm Hg in diastolic BP in the supine position.

KEY FINDING: NSC from E14 mice on multichannel PLG scaffold increases density of axons and myelin regeneration and leads to a more rapid and functional recovery

KEY FINDING: Single-cell RNA sequencing has identified latent lineage potential in neural stem cells (NSCs) in the spinal cord's ependymal region to differentiate into oligodendrocytes by regulating OLIG2 expression.

KEY FINDING: Satellite cells from spinal cord-injured individuals retain the capacity to differentiate into myotubes.