Browse our collection of 11,526 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 3,981-3,990 of 11,526 results
Frontiers in Neurorobotics, 2021 • October 7, 2021
This paper introduces TWIN, a modular lower limb exoskeleton developed using a user-centered design approach. The design process involved patients, engineers, and clinicians to identify key requiremen...
KEY FINDING: The study found that a user-centered design approach, involving patients and clinicians, was effective in developing an exoskeleton that addresses user needs.
Qatar Medical Journal, 2021 • October 7, 2021
This study examines SCIWORA in adults, a condition where spinal cord injury occurs without visible bone damage on initial X-rays or CT scans. The study reviews 11 cases to understand the clinical feat...
KEY FINDING: The majority of SCIWORA patients in this series were males with a mean age of 46.5 years, with falls being the most common injury mechanism.
Spinal Cord Series and Cases, 2021 • October 7, 2021
This document is a correction to a previously published article. The correction pertains to Figure 6, which was displayed incorrectly in the original publication. The document provides the corrected f...
KEY FINDING: The original article contained an incorrect Figure 6.
Cells, 2021 • October 7, 2021
This study systematically reviews experimental treatments for oedema following spinal cord injury (SCI). It identifies key modalities such as selective inhibition of aquaporin 4 (AQP4), modulation of ...
KEY FINDING: Selective inhibition of aquaporin 4 (AQP4), modulation of inflammation, and surgical interventions are key modalities that attenuate oedema following spinal cord injury.
Cells, 2021 • October 6, 2021
This review discusses the multifaceted pathophysiology of SCI and the potential of stem cell therapy, advocating for precision medicine approaches. It categorizes stem cell therapies into supportive a...
KEY FINDING: SCI pathophysiology is multifaceted, necessitating treatments that address dynamic interactions between various cell types. Stem cells are suited for this purpose due to their ability to duplicate, differentiate, and secrete trophic factors.
Physiological Reports, 2021 • October 6, 2021
The study investigated the effects of dose de-escalation (DD) of testosterone and evoked resistance training (RT) on body composition, cardiometabolic, and neuromuscular variables in men with spinal c...
KEY FINDING: Absolute thigh muscle cross-sectional areas decreased in the group that underwent testosterone treatment and resistance training, while it increased in the group that received no treatment.
Theranostics, 2021 • October 3, 2021
This study investigates the effects of IL-13 and IL-4 administration after SCI on microglia and macrophage phenotype and functional outcomes. The results reveal that the metabolic fitness of microglia...
KEY FINDING: IL-13 induced the expression of anti-inflammatory markers in microglia and macrophages after SCI but, in contrast to IL-4, it failed to mediate functional recovery.
Sensors, 2021 • October 2, 2021
This study investigates the feasibility of EEG monitoring during transcutaneous electrical spinal cord stimulation (tSCS) by characterizing artifacts and evaluating artifact-suppression techniques. Th...
KEY FINDING: tSCS manifested as narrow, high-amplitude peaks in the time domain at a rate equal to the stimulation frequency, making the EEG nearly an order of magnitude more powerful than normal EEG.
Spinal Cord, 2021 • October 1, 2021
This study explored barriers and facilitators to weight management among individuals with SCI from the perspectives of SCI healthcare providers. Providers identified individual-level, socio-environmen...
KEY FINDING: Healthcare providers identified numerous individual-level barriers such as physical limitations, lack of interest, and psychological factors.
Magn Reson Med, 2021 • October 1, 2021
This study demonstrates the feasibility of spinal cord fMRI during SCS in rats using MB-SWIFT to overcome obstacles associated with spinal cord imaging. High-quality fMRI of the rat spinal cord was pe...
KEY FINDING: MB-SWIFT was tolerant to electrode-induced artifacts and respiratory motion, leading to substantially higher fMRI sensitivity than spin echo fMRI.