Browse the latest research summaries in the field of musculoskeletal medicine for spinal cord injury patients and caregivers.
Showing 31-40 of 269 results
Interventional Pain Medicine, 2023 • January 2, 2023
This case report describes an 83-year-old male who developed anterior spinal artery syndrome (ASAS) nine days after undergoing kyphoplasty for a T8 vertebral compression fracture. The ASAS was caused ...
KEY FINDING: A rare case of delayed-onset ASAS occurred nine days after kyphoplasty, caused by retropulsion of a bone fragment from a refractured vertebral body.
Rev Bras Ortop, 2024 • September 4, 2024
This study showed that applying NMES for 5 weeks prevents biceps brachii muscle atrophy after incomplete cervical SCI. Additionally, this therapy prevents loss in IL-6 levels, a potential stimulation ...
KEY FINDING: NMES prevents biceps brachii muscle atrophy after incomplete cervical SCI in rats.
BMJ Open, 2024 • March 4, 2024
This study protocol outlines a randomized controlled trial to investigate the effects of exoskeletal-assisted walking (EAW) alone versus EAW combined with transcutaneous spinal cord stimulation (tSCS)...
KEY FINDING: The combination of EAW+tSCS may promote a more reciprocal firing pattern for the flexors and extensors than EAW alone resulting in increased functional joint torque contribution of the lower limb.
Calcified Tissue International, 2024 • September 25, 2024
This study evaluated the impact of early zoledronic acid (ZOL) infusion on bone mineral density (BMD) in acute traumatic spinal cord injury (TSCI) patients compared to chronic TSCI patients. The findi...
KEY FINDING: Acute TSCI patients had higher bone turnover markers and sclerostin concentrations at baseline compared to chronic TSCI patients.
Medicine, 2024 • September 30, 2024
This study aimed to clarify long-term bone loss from the acute (within 12 months) to the chronic (over 12 months) phase in hundreds of individuals with SCI and to identify both demographic and SCI-rel...
KEY FINDING: Substantial annual bone loss occurred in the total hip site up to 3 years postinjury and in the femoral neck site up to 2 years postinjury.
BMC Musculoskeletal Disorders, 2024 • September 23, 2024
This study validated the structural validity of the BARQ-R using Rasch analysis in community-dwelling adults with and without musculoskeletal pain in the US, and validated previous Rasch analysis resu...
KEY FINDING: The 9-item Rasch-based BARQ-R had no misfitting items after rescoring 1 item and deleting 3 items in community-dwelling adults with and without musculoskeletal pain.
World Journal of Orthopedics, 2024 • October 18, 2024
This study analyzes research trends in exercise therapy (ET) for pain management in postmenopausal osteoporosis (PMOP) patients over the last decade using bibliometric analysis. Key findings include a...
KEY FINDING: There was a rapid increase in annual publication output in 2015, followed by stable growth in subsequent years, indicating growing scholarly attention.
Molecular Medicine, 2024 • November 7, 2024
This study investigates the causal relationship between mitochondrial abnormalities and chronic post-sepsis muscle weakness, exploring potential therapeutic targets. The findings demonstrate that post...
KEY FINDING: Post-sepsis skeletal muscle weakness develops progressively after the resolution of acute sepsis and is linked to mitochondrial abnormalities.
SAGE Open Medical Case Reports, 2024 • November 5, 2024
This case report presents the results of multiple dual-energy X-ray absorptiometry scans conducted over 14 years, highlighting changes in bone mineral density (BMD). The individual studied maintained ...
KEY FINDING: An individual with chronic complete SCI maintained and, in some areas, increased BMD in the lower extremities over 14 years.
Cell Reports Medicine, 2024 • December 17, 2024
This study investigates why severe injury to the central nervous system (CNS) triggers the development of large neurogenic heterotopic ossifications (NHOs) within periarticular muscles. The central rol...
KEY FINDING: Severe SCI causes a spike in blood corticosterone in mice, which is causal for NHO development.