Browse the latest research summaries in the field of musculoskeletal medicine for spinal cord injury patients and caregivers.
Showing 21-30 of 269 results
BMC Musculoskeletal Disorders, 2024 • January 9, 2024
This retrospective, cross-sectional study compared osteoporosis prevalence in Korean adults with SCI using different BMDRV: region-based from DXA manufacturers (TDXA) and international based on NHANES...
KEY FINDING: The prevalence of osteoporosis was significantly higher using the NHANES III reference (TNHA) compared to the DXA manufacturer's reference (TDXA) in both males and females.
Cancer Medicine, 2024 • January 1, 2024
This retrospective study investigated the incidence and risk factors of skeletal-related events (SREs) in 146 patients with Ewing sarcoma (EWS) treated at a single institution between 2005 and 2019. T...
KEY FINDING: SREs occurred in 23 patients during the study period, with radiation to the bone and malignant spinal cord compression being the most frequent initial events.
Virtual Reality, 2024 • April 7, 2024
This systematic review aimed to find effective virtual rehabilitation methods for physical improvement and engagement in people with osteoporosis or musculoskeletal disorders. The review identified fo...
KEY FINDING: Different virtual rehabilitation devices offer varying degrees of immersion and physical improvement.
Journal of Cachexia, Sarcopenia and Muscle, 2024 • May 19, 2024
This study investigates the time course of molecular changes in rat soleus muscle following severe spinal cord injury (SCI) to identify therapeutic targets and windows for treating muscle wasting. The...
KEY FINDING: SCI induces early and transient expression of extracellular matrix (ECM) remodeling genes, leading to muscle fibrosis.
Frontiers in Pharmacology, 2024 • May 15, 2024
This editorial highlights the potential of natural products, medicinal foods, and herbal medicines in treating bone metabolism diseases and bone-related tumors. The included research articles explore ...
KEY FINDING: Tea-Seed Oil (TSO) contains components with antibacterial properties, potentially acting through pathways like PI3K-AKT and MAPK.
JBMR Plus, 2024 • June 7, 2024
One year of romosozumab treatment in women with chronic SCI increased DXA-derived aBMD at the lumbar spine and hip. These results were congruent with CT results at the hip, which indicated increases i...
KEY FINDING: After 12 mo of treatment, areal BMD at the lumbar spine and total hip were significantly increased with median changes of 10.2% (IQR: 8.3–15.2%, p<.001) and 4.2% (IQR: 3.4–7.7%, p = .009), respectively.
J. Funct. Morphol. Kinesiol., 2024 • June 20, 2024
This study assessed neuromuscular fatigue by comparing rapid force production in elbow flexors and extensors between athletes with amputation (AMP) and spinal cord injury (SCI). SCI athletes exhibited...
KEY FINDING: SCI athletes had lower MVF and RFDpeak values than AMP athletes.
Front. Rehabil. Sci., 2024 • July 16, 2024
The project successfully co-developed and disseminated a series of nine educational podcasts and related EATs, titled “The Bare Bones Podcast Series,” to educate individuals with SCI/D about bone heal...
KEY FINDING: Nine podcast episodes and related Educational Action Planning Tools (EATs) were co-developed with PLEX partners, reviewers, and expert panel members.
Bioengineering, 2024 • August 12, 2024
This study investigated the effects of BWSTT and neurotrophin-releasing scaffolds, alone and in combination, on bone loss following spinal cord injury (SCI) in rats. The study found that BWSTT and the...
KEY FINDING: BWSTT and combinational groups reported higher biomechanical properties in the tibial bone (below injury level) when compared to the injury and scaffold groups.
Journal of Musculoskeletal and Neuronal Interactions, 2024 • July 18, 2024
This paper presents a narrative review of research findings on the disturbance of the typical balance between muscles and bones caused by acute muscle paralysis from BTX, resulting in osteopenia and b...
KEY FINDING: BTX might exert a direct influence on bone resorption.