Browse the latest research summaries in the field of oncology for spinal cord injury patients and caregivers.
Showing 121-130 of 144 results
BMC Pediatrics, 2018 • March 26, 2018
This case report highlights a rare presentation of a germ cell tumor (GCT) in the posterior mediastinum of a child, leading to spinal cord compression and paraparesis. The child was treated with a com...
KEY FINDING: The patient presented with progressive back pain, leg weakness, and was found to have a large mass in the posterior mediastinum compressing the spinal cord.
Neural Regen Res, 2013 • June 1, 2013
This study investigated the effects of X-irradiation on glial scar formation and functional recovery in rats with spinal cord injury. The researchers aimed to determine the optimal time window for X-i...
KEY FINDING: X-irradiation at 8 Gy reduced the expression of macrophage marker ED-1, indicating a decrease in inflammation.
Journal of Nanobiotechnology, 2022 • December 28, 2022
The study developed CaO2@mPDA-SH nanoparticles that can regulate the tumor microenvironment by consuming lactic acid and alleviating hypoxia. The nanoparticles promote immune responses, inhibit angio...
KEY FINDING: CaO2@mPDA-SH nanoparticles can dually regulate tumor hypoxia and lactic acid metabolism.
Frontiers in Immunology, 2024 • July 4, 2024
This study demonstrates that MVP is markedly increased in PAAD tissues and correlated with an adverse prognosis. Related analyses confirmed its potential as a novel diagnostic and prognostic indicator...
KEY FINDING: MVP is abnormally upregulated in PAAD tissues and correlates with adverse prognosis.
Communications Biology, 2024 • December 2, 2024
The study provides a single-cell level atlas characterizing the tumor microenvironment (TME) in primary and recurrent multifocal bladder cancer (BLCA). Analyses reveal significant differences in malig...
KEY FINDING: Malignant cells from recurrent multifocal bladder cancer exhibited higher interregional transcriptional similarity and consistent cellular communication.
Strahlentherapie und Onkologie, 2024 • August 29, 2024
The study evaluates the feasibility and toxicity of robustly optimized intensity-modulated proton therapy (IMPT) in treating skull base chordoma and chondrosarcoma. The results indicate that IMPT is a...
KEY FINDING: Robustly optimized IMPT is clinically feasible as a postoperative treatment for skull base chordoma and chondrosarcoma patients.
npj Genomic Medicine, 2022 • August 8, 2022
Based on TCGA and TCGASpliceSeq databases, gene expression and the AS data of UCEC samples were retrieved. These findings indicate that HSPB1, a splicing factor, regulates the expression of ANKHD1-BP3 ...
KEY FINDING: An alternate terminator of ANKHD1 transcripts named ANKHD1-BP3 was found to be significantly related to metastasis and OS in UCEC and significantly associated with HSPB1.
Advanced Science, 2023 • March 12, 2023
This review discusses the role of bacteria in tumorigenesis, the latest advances in bacteria-based delivery platforms, and the existing obstacles for application. The review summarizes the application...
KEY FINDING: Certain types of tumor have their own unique microbial composition, which has an important role in the survival of cancer patients.
JOURNAL OF WOMEN’S HEALTH, 2011 • January 1, 2011
Mobility impairments can affect women at every point during early-stage breast cancer diagnosis, therapy, and recovery. Clinicians must consider women’s mobility functioning in making therapeutic reco...
KEY FINDING: Inaccessible equipment was a primary problem during mammograms, especially for women who could not stand.
The Journal of Spinal Cord Medicine, 2018 • September 1, 2018
This case report describes the development of acute promyelocytic leukemia (APL) in a 47-year-old male with tetraplegia during inpatient rehabilitation. The patient presented with fever, thrombocytope...
KEY FINDING: A patient with tetraplegia developed acute promyelocytic leukemia (APL) while undergoing inpatient rehabilitation.