Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 31-40 of 555 results
Cureus, 2023 • July 29, 2023
This systematic review investigates various pharmaceutical and non-pharmaceutical interventions for managing pain in patients after spinal cord injury. The review included 57 studies, evaluating oral ...
KEY FINDING: Gabapentin and pregabalin are effective for managing chronic neuropathic pain post-SCI, with pregabalin also potentially reducing anxiety and sleep disturbances. Lamotrigine, valproate, and carbamazepine were found ineffective.
J. Clin. Med., 2023 • September 4, 2023
This study investigated the impact of immersive virtual reality walking (VRWalk) on neuropathic pain (NP) following spinal cord injury (SCI), focusing on changes in thalamic GABA content. The findings...
KEY FINDING: Participants showed a significant decrease in NRS ratings of average pain collected prior to and following the intervention.
Front. Physiol., 2023 • August 31, 2023
This study investigated the feasibility and potential efficacy of remotely delivered Spring Forest Qigong for reducing neuropathic pain in adults with spinal cord injury (SCI). The results demonstrate...
KEY FINDING: Remote Spring Forest Qigong is feasible for adults with SCI-related neuropathic pain, with high adherence and no study-related adverse events.
African Journal of Primary Health Care & Family Medicine, 2023 • October 26, 2023
This study developed a pain self-management intervention framework for PWSCI using a modified e-Delphi method with a panel of experts. The framework includes 56 interventions spanning medical, psychol...
KEY FINDING: The final pain self-management framework consists of 56 interventions, encompassing medical, psychological, therapeutic, and social approaches.
The Journal of Spinal Cord Medicine, 2025 • November 17, 2023
This study investigated the effects of iTBS and high-frequency rTMS on SCI-related neuropathic pain compared to a sham control group. The results showed that both real iTBS and real rTMS significantly...
KEY FINDING: Both real iTBS and real rTMS significantly reduced pain compared to the sham rTMS group, according to all pain evaluation tools used.
Cureus, 2023 • November 5, 2023
The study aimed to delineate the national landscape concerning pain management for botulinum toxin type A injections in pediatric patients and to formulate a protocol grounded in current scientific ev...
KEY FINDING: There is a concern among specialists about managing pain caused by BoNT-A injections in children.
Sports Medicine - Open, 2023 • October 8, 2023
This study compared neuropathic pain experiences among Paralympic versus recreational athletes with SCI, finding that Paralympic athletes reported greater neuropathic pain intensity but also higher le...
KEY FINDING: Paralympic athletes reported significantly greater neuropathic pain intensity than recreational athletes.
Molecular Pain, 2024 • January 1, 2024
This study investigates the therapeutic effects of Kilohertz High Frequency Electrical Stimulation (KHES) on neuropathic pain in mice, focusing on the TRPV1/NMDAR2B signaling pathway. The results demo...
KEY FINDING: KHES significantly alleviated mechanical and thermal allodynia in neuropathic pain mice, demonstrating its potential as a treatment.
bioRxiv preprint, 2023 • December 14, 2023
The study demonstrates that a triple combination formulation (TCF) containing the HDAC inhibitor vorinostat can effectively treat chronic neuropathic pain in a spared nerve injury (SNI) rat model. A s...
KEY FINDING: A single injection of the TCF significantly reduced mechanical allodynia (pain from normally non-painful stimuli) for up to four weeks in SNI rats.
Anesth Analg, 2024 • October 1, 2024
The study demonstrates that exercise can alleviate neuropathic pain in mice by affecting astrocytes, a type of cell in the spinal cord. Exercise reduces the activity of these astrocytes and normalizes...
KEY FINDING: Exercise training reversed mechanical and cold allodynia and improved pain-related gait behaviors in an SNI-induced neuropathic pain mice model.