Browse the latest research summaries in the field of cardiovascular science for spinal cord injury patients and caregivers.
Showing 251-260 of 309 results
J. Phys. Ther. Sci., 2019 • August 1, 2019
The study investigated the prevalence of DVT, muscle thickness, TAMV during passive ankle exercise, and venous diameter in patients with chronic paraplegia. All chronic SCI patients had asymptomatic D...
KEY FINDING: Chronic SCI patients had significant leg muscle atrophy, with muscle thickness being 67.2% that of able-bodied participants.
Interdiscip CardioVasc Thorac Surg, 2025 • February 5, 2025
This study reports the outcomes of open thoraco-abdominal aortic aneurysm (TAAA) repair at a single academic medical center from 2015 to 2023, involving 190 patients. The primary endpoint was operativ...
KEY FINDING: Operative mortality was 7.9%, with similar rates in elective (7.5%) and non-elective (9.1%) cases.
J Physiol, 2025 • March 22, 2025
This study investigated the roles of the autonomic nervous system in cardiac dysfunction following spinal cord injury (SCI) in rats, finding that impaired sympathetic control is the primary driver. Th...
KEY FINDING: Impaired direct sympathetic transmission to the heart underlies the majority of the SCI-induced reduction in heart function post-SCI.
J. Anat., 1966 • January 1, 1966
The study used Monastral fast blue injections to visualize the development and regeneration of blood vessels in Xenopus laevis. A tree-like vascular pattern was found in the spinal cord and rhombencep...
KEY FINDING: A tree-like vascular pattern is observed specifically in the spinal cord and rhombencephalon (hindbrain) of Xenopus laevis.
International Journal of Molecular Sciences, 2021 • April 9, 2021
This study demonstrates that both cell culture oxygen conditions and the mode of EV preparation significantly affect the function of human iPSC-EVs. Hypoxic conditioning of human iPSCs resulted in the...
KEY FINDING: iPSC-EVs derived from 1% oxygen culture exhibit significantly elevated angiogenic potential compared to EVs obtained at higher oxygen levels.
PM R, 2018 • April 1, 2018
This study examined the relationship between testosterone levels and cardiometabolic risk factors in young men with chronic spinal cord injury (SCI). It found that low testosterone levels are associat...
KEY FINDING: Men with low free testosterone had significantly higher Framingham Risk Scores, indicating a greater risk of cardiovascular events.
Top Spinal Cord Inj Rehabil, 2014 • April 1, 2014
The secondary conditions of metabolic syndrome and cardiovascular disease (CVD) resulting from spinal cord injury (SCI ) are not well understood. Carotid intima-media thickness (CIMT) is the most robu...
KEY FINDING: Several variables were significantly correlated with CIMT during univariate analyses, including glucose, hemoglobin A1c, age, and race/ethnicity; but only age was significant in the hierarchical regression analysis.
Cellular and Molecular Neurobiology, 2004 • June 1, 2004
This study used nestin and Fluoro-Jade B to study the regional differences between ischemic and IPC-induced changes of ependyma and the gray matter of rat lumbosacral spinal cord. The study demonstrat...
KEY FINDING: Twelve-minute ischemia induced nestin positivity in ependyma and reactive astrocytes at the L1−3 spinal cord segments. This identifies the L1-L3 region as viable after the ischemic event.
Nat Med, 2017 • June 1, 2017
This study demonstrates that pericytes play a major role in regulating capillary tone and blood flow in the spinal cord after SCI, leading to chronic hypoxia. The researchers found that AADC expressed...
KEY FINDING: SCI leads to chronic hypoxia in the spinal cord below the injury site due to excessive capillary tone.
Frontiers in Neuroscience, 2020 • March 3, 2020
This study investigated the role of platelets in Alzheimer's disease (AD) using APP-PS1 transgenic mice, which exhibit severe amyloid plaque formation. The research focused on the presence, location, ...
KEY FINDING: APP-PS1 mice showed a higher number of platelets in the brain parenchyma compared to WT controls, indicating platelet invasion into the brain.