Browse the latest research summaries in the field of endocrinology for spinal cord injury patients and caregivers.
Showing 201-210 of 211 results
iScience, 2023 • January 20, 2023
This study investigates the metabolic mechanisms underlying artemisinin resistance (ART-R) in Plasmodium falciparum, focusing on the role of PfKelch13 mutations and ring-stage growth arrest. The resea...
KEY FINDING: PfKelch13 mutant parasite lines exhibit reduced susceptibility to DHA and prolonged ring stage.
Oxidative Medicine and Cellular Longevity, 2021 • July 31, 2021
Our results sug- gested that zinc enhanced the glucose uptake of the injured neurons and spinal cord, reduced oxidative stress and neuro- nal apoptosis, promoted mitochondrial biogenesis, and encourag...
KEY FINDING: zinc elevated the expression level of GLUT4 and promoted glucose uptake.
The Journal of Spinal Cord Medicine, 2017 • September 1, 2017
This retrospective study analyzed serum lipid profiles in 269 SCI patients, correlating them with disease duration, lesion level/grade, and ambulation status to assess dyslipidemia risk factors. The s...
KEY FINDING: Total cholesterol, LDL cholesterol, and triglycerides were higher than normal in 21.2%, 24.4%, and 31% of the patients, respectively.
The Journal of Spinal Cord Medicine, 2018 • July 1, 2018
The study examined the effect of level of spinal cord injury (LOI) on adipose tissue, proinflammatory adipokines, and cardiometabolic profiles in individuals with motor complete SCI. Results indicated...
KEY FINDING: The study found that the level of injury did not significantly influence the distribution of adipose tissue.
Physiol Rep, 2018 • August 1, 2018
This pilot study compared the effects of an 8-week high-protein diet versus a combined exercise regimen on metabolic health in individuals with long-standing spinal cord injury (SCI). Both the high-pr...
KEY FINDING: Fasting plasma glucose levels decreased in the combined exercise group compared to the high-protein diet group.
Lipids in Health and Disease, 2023 • October 2, 2023
This study identified a novel frameshift insertion in the LDLR gene and several variants in the APOB gene in a Chinese family with familial hypercholesterolemia. The cumulative effect of these genetic...
KEY FINDING: A novel frameshift insertion (c.497delinsGGATCCCCCAGCTGCATCCCCCAG: p. Ala166fs) was identified in the LDLR gene, preventing proper expression of LDLR on the cell membrane.
Cardiovasc Diabetol, 2018 • May 10, 2018
This study investigated the effect of linagliptin on endothelial function and postprandial lipid levels in subjects with coronary artery disease (CAD) and early type 2 diabetes mellitus (T2DM). The re...
KEY FINDING: Linagliptin treatment did not significantly improve flow mediated dilation (FMD) in patients with CAD and early T2DM compared to placebo.
J Neurol Neurosurg Psychiatry, 2001 • July 1, 2001
Obesity is linked to increased intracranial pressure through mechanisms such as raised intra-abdominal and intrathoracic pressures. IIH is a heterogeneous condition, with obesity being a potential ris...
KEY FINDING: Obesity is likely only one of several risk factors for IIH, as obesity is common while IIH is rare and affects genders differently.
J Spinal Cord Med, 2006 • January 1, 2006
This case report describes a 21-year-old man with a C6 spinal cord injury who developed adrenal insufficiency two weeks after the injury. The patient's adrenal insufficiency complicated his rehabilita...
KEY FINDING: The patient developed symptomatic hypotension resistant to vasopressors and volume replacement 2 weeks after injury and was diagnosed with adrenal insufficiency.
Neural Regeneration Research, 2017 • December 1, 2017
This review explores techniques for quantifying intermuscular (IMAT) and intramuscular (IntraMAT) adipose tissue using MRI, highlighting inconsistencies in past studies. It compares the Otsu and Midpo...
KEY FINDING: Significant differences exist between the Midpoint and Otsu methods in quantifying intramuscular adipose tissue (%IntraMAT) in the knee extensor muscle group.