Browse the latest research summaries in the field of musculoskeletal medicine for spinal cord injury patients and caregivers.
Showing 11-20 of 269 results
BMC Musculoskeletal Disorders, 2024 • October 21, 2024
This retrospective study compared the efficacy of ROI-C and conventional cage-plate (CCP) in improving cervical stability in patients with spinal cord injury without fracture or dislocation (SCIWFD). ...
KEY FINDING: Both ROI-C and CCP groups achieved bony fusion at the final follow-up, indicating similar efficacy in promoting spinal stability.
Journal of Musculoskeletal and Neuronal Interactions, 2023 • September 1, 2023
The case report presents a 68-year-old man who developed Pellegrini-Stieda disease (PSD) following a severe accident resulting in spinal cord injury, despite the absence of direct knee trauma. The pat...
KEY FINDING: This case report highlights an unusual presentation of Pellegrini-Stieda disease in a patient with a spinal cord injury but without recent knee trauma.
Biomedicines, 2023 • September 20, 2023
Spinal cord injury (SCI) leads to neurogenic bone loss, predisposing individuals to osteoporosis and fractures, significantly limiting physical and functional capacity. Pharmacological treatments like...
KEY FINDING: Immobility and de-loading after SCI increase bone resorption and decrease osteoblast activity, resulting in osteopenia.
The Journal of Spinal Cord Medicine, 2025 • September 27, 2023
This study investigates the age-dependent effects of vitamin D supplementation on musculoskeletal health in chronic SCI patients with vitamin D deficiency. The results indicate that vitamin D suppleme...
KEY FINDING: In younger adults with SCI, vitamin D supplementation led to significant improvements in testosterone, total cholesterol, and triglyceride levels.
Frontiers in Physiology, 2023 • October 18, 2023
This study investigated changes in performance and perceived fatigability during a wheelchair propulsion fatigue protocol (F8F) in individuals with paraplegia. The results showed significant increases...
KEY FINDING: Heart rate and perceived exertion significantly increased during the wheelchair propulsion fatigue protocol.
Nutrients, 2023 • October 28, 2023
This study explored the potential benefits of combining GlyNAC supplementation with body weight support treadmill training (BWSTT) for rats with spinal cord injury (SCI). The primary focus was on asse...
KEY FINDING: GlyNAC alone improved motor function, as indicated by BBB scores, gait symmetry, and open field test results.
The Journal of Spinal Cord Medicine, 2024 • January 1, 2024
This study explored the knowledge and awareness of bone loss and fracture risk among adults with SCI. It revealed that a significant portion of participants were unfamiliar with BMD and felt their kno...
KEY FINDING: Approximately 20% of participants had never heard of bone mineral density (BMD).
Inflammation, 2024 • April 1, 2024
This study investigates the therapeutic potential of GlyNAC (glycine and N-acetylcysteine) in treating spinal cord injury (SCI) by reducing oxidative stress and skeletal muscle atrophy in a rat model....
KEY FINDING: GlyNAC treatment significantly elevated BBB scores from the first to the eighth week after intervention, suggesting improved motor function recovery in rats with SCI.
JBMR Plus, 2023 • December 1, 2023
The study demonstrates the efficacy of Siglec-15 Ab (NP159) in reducing bone resorption after acute SCI while maintaining bone formation capacity in rats. NP159 almost fully prevents the SCI-induced l...
KEY FINDING: NP159 treatment almost completely prevents the deterioration of bone after SCI, including loss of bone mineral density, trabecular bone volume, trabecular connectivity, and bone stiffness.
Top Spinal Cord Inj Rehabil, 2023 • January 1, 2023
The study developed SCI-FX, a preliminary risk score to estimate 5-year lower extremity fragility fracture risk among patients living with chronic spinal cord injury (cSCI). The model incorporates fac...
KEY FINDING: A simple model was identified to estimate 5-year fracture risk among patients with cSCI based on their total score.